Catálogo de publicaciones - revistas

<jats:p>The spatial and temporal organization of molecules within a cell is critical for coordinating the many distinct activities carried out by the cell. In an increasing number of biological signaling processes, scaffold proteins have been found to play a central role in physically assembling the relevant molecular components. Although most scaffolds use a simple tethering mechanism to increase the efficiency of interaction between individual partner molecules, these proteins can also exert complex allosteric control over their partners and are themselves the target of regulation. Scaffold proteins offer a simple, flexible strategy for regulating selectivity in pathways, shaping output behaviors, and achieving new responses from preexisting signaling components. As a result, scaffold proteins have been exploited by evolution, pathogens, and cellular engineers to reshape cellular behavior.</jats:p>

<jats:p>Simultaneous measurement of more than 30 properties in individual human cells is used to characterize signaling in the immune system.</jats:p>

<jats:p>Resonant x-ray scattering is used to detect microscopic loop currents within the plane of cupric oxide.</jats:p>

<jats:p>Inelastic x-ray scattering probed the doping dependence of the electronic environment within a cuprate superconductor.</jats:p>

<jats:p>An active optical antenna-diode combines the functions of light-harvesting and excited-electron injection.</jats:p>

<jats:p>Comparison of eye structures between fossils and modern species suggests that Mesozoic archosaurs were active day and night.</jats:p>

<jats:p>Spacecraft observations show that Saturn’s and Jupiter’s rings preserve records of recent interplanetary debris collisions.</jats:p>

<jats:p>Spacecraft observations show that Saturn’s and Jupiter’s rings preserve records of recent interplanetary debris collisions.</jats:p>

<jats:p>Marine protist cells from the wild environment contain DNA from several viruses and bacteria, but apparently lack plastids.</jats:p>

<jats:p>Guanylate-binding proteins coordinately regulate oxidative and autophagic responses to intracellular bacteria.</jats:p>