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Science

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

ER Tubules Mark Sites of Mitochondrial Division

Jonathan R. Friedman; Laura L. Lackner; Matthew West; Jared R. DiBenedetto; Jodi Nunnari; Gia K. Voeltz

<jats:p>Mitochondrial division occurs at positions where endoplasmic reticulum tubules contact mitochondria and mediate constriction.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 358-362

Antimicrobial Peptides Keep Insect Endosymbionts Under Control

Frédéric H. Login; Séverine Balmand; Agnès Vallier; Carole Vincent-Monégat; Aurélien Vigneron; Michèle Weiss-Gayet; Didier Rochat; Abdelaziz Heddi

<jats:p>A beetle species synthesizes an antimicrobial peptide to constrain a bacterial symbiont in specialized organs.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 362-365

Stochastic Pulse Regulation in Bacterial Stress Response

James C. W. Locke; Jonathan W. Young; Michelle Fontes; María Jesús Hernández Jiménez; Michael B. Elowitz

<jats:p>Energy stress activates an alternative sigma factor in stochastic pulses and modulates pulse frequency to control activity.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 366-369

Transgenerational Epigenetic Instability Is a Source of Novel Methylation Variants

Robert J. Schmitz; Matthew D. Schultz; Mathew G. Lewsey; Ronan C. O’Malley; Mark A. Urich; Ondrej Libiger; Nicholas J. Schork; Joseph R. Ecker

<jats:p> Spontaneous methylation rates that may affect phenotype in the plant <jats:italic>Arabidopsis</jats:italic> are higher than the mutation rate. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 369-373

Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Mihai L. Azoitei; Bruno E. Correia; Yih-En Andrew Ban; Chris Carrico; Oleksandr Kalyuzhniy; Lei Chen; Alexandria Schroeter; Po-Ssu Huang; Jason S. McLellan; Peter D. Kwong; David Baker; Roland K. Strong; William R. Schief

<jats:p>A two-segment HIV epitope grafted into a scaffold protein maintains high affinity for a broadly neutralizing antibody.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 373-376

Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination

Erin C. Dueber; Allyn J. Schoeffler; Andreas Lingel; J. Michael Elliott; Anna V. Fedorova; Anthony M. Giannetti; Kerry Zobel; Brigitte Maurer; Eugene Varfolomeev; Ping Wu; Heidi J. A. Wallweber; Sarah G. Hymowitz; Kurt Deshayes; Domagoj Vucic; Wayne J. Fairbrother

<jats:p>Antagonist binding to an apoptosis inhibitor releases inhibition by promoting dimerization required for autoubiquitination.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 376-380

Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding

Min Zhou; Nina Morgner; Nelson P. Barrera; Argyris Politis; Shoshanna C Isaacson; Dijana Matak-Vinković; Takeshi Murata; Ricardo A. Bernal; Daniela Stock; Carol V. Robinson

<jats:p>The effect of lipids and nucleotides on the soluble head domain and membrane base domain is examined in an intact adenosine triphosphatase.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 380-385

Cerebellum Shapes Hippocampal Spatial Code

Christelle Rochefort; Arnaud Arabo; Marion André; Bruno Poucet; Etienne Save; Laure Rondi-Reig

<jats:p>Cerebellar protein kinase C–dependent mechanisms process self-motion information needed for spatial representation and accurate navigation.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 385-389

Activity-Dependent Long-Term Depression of Electrical Synapses

Julie S. Haas; Baltazar Zavala; Carole E. Landisman

<jats:p>Paired bursting in coupled neurons depresses electrical synapses while their asymmetry increases after unidirectional use. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 389-393

Science Podcast

<jats:p>The show includes mastodon hunting before Clovis, globalization and West Nile virus, the search for the "sterile neutrino," and more.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 395-395