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<jats:p>At the end of every year, we take a look back at some of our favorite and most popular stories. This year's top 10 includes our most read story of all time.</jats:p>

<jats:p>Last week's $915 billion spending bill for fiscal year 2012 treats science as well as, if not better than, most other federal activities.</jats:p>

<jats:p>A recent meeting provided fresh insights into why HIV is so difficult to eliminate from the body: Even when antiretroviral drugs knock down HIV to undetectable levels in blood, the virus remains active in tissues.</jats:p>

<jats:p>Scientists have identified a drug that, in mice, fixes the genetic defect behind Angelman syndrome, which robs victims of speech and leaves them with intellectual disabilities, movement and balance problems.</jats:p>

<jats:p>Climate models are bigger and more sophisticated than ever, speakers reported at the meeting, but they are yielding the same wide range of possible warming and precipitation changes as they did 5 years ago.</jats:p>

<jats:p>Dawn spacecraft scientists probing Vesta's interior for the first time reported at the meeting that they had detected a metallic core to the rocky asteroid.</jats:p>

<jats:p>Researchers reported at the meeting that the redistributed stress of March's magnitude-9 Tohoku earthquake activated distant, long-quiescent faults, the first time that has been recorded.</jats:p>

<jats:p>Snapshots from the meeting include a report that studies suggesting that the world's energy needs could be met by biofuels are far too optimistic and a spot on the floor of the eastern tropical Pacific where oceanographers can track the changing pressure of the overlying water accurately enough to gauge the changing mass of the world ocean.</jats:p>