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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Guided Tour to the Heart of RISC

Emine Kaya; Jennifer A. Doudna

<jats:p>The crystal structures of human and yeast Argonaute proteins reveal the intricacies of the multidomain enzyme at the hub of the RNA interference machinery.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 985-986

Resolving Some Old Problems in Protein Crystallography

Phil Evans

<jats:p>Two methods improve the quality and ease of structural modeling by showing how to include diffraction data that are often thrown away.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 986-987

Kinship and Human Thought

Stephen C. Levinson

<jats:p>Language and communication are central to shaping concepts such as kinship categories.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 988-989

Enter the Majorana Fermion

Piet W. Brouwer

<jats:p>Electrical measurements on a semiconductor–superconductor hybrid structure reveal the signature of this long-predicted exotic particle.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 989-990

Systems Biology, Metabolomics, and Cancer Metabolism

Masaru Tomita; Kenjiro Kami

<jats:p>Constructing metabolic profiles of 60 cancer cell lines by integrating metabolomics and systems biology revealed increased glycine consumption in highly proliferative cancer cells.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 990-991

An Avian Magnetometer

Michael Winklhofer

<jats:p>Neurons in the pigeon brain encode information on Earth's magnetic field for orientation and navigation.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 991-992

Learning Biology by Recreating and Extending Mathematical Models

Hillel J. Chiel; Jeffrey P. Gill; Jeffrey M. McManus; Kendrick M. Shaw

<jats:p>Dynamics of Biological Systems, the IBI Prize–winning module, brings mathematics into the biology laboratory.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 993-994

AAAS News and Notes

<jats:p> A monthly roundup of recent news and projects of <jats:italic>Science</jats:italic> 's publisher, the American Association for the Advancement of Science. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 997-997

Predicting Pragmatic Reasoning in Language Games

Michael C. Frank; Noah D. Goodman

<jats:title>Who's Who</jats:title> <jats:p> Different languages rely on distinct sets of terminology to classify relatives, such as maternal grandfather in English, and precision in language usage is a key component for successful communication (see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6084" page="988" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1222691">Levinson</jats:related-article> </jats:bold> ). <jats:bold>Kemp and Regier</jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1049" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1218811">1049</jats:related-article> ) propose an organizing framework whereby kinship classification systems can all be seen to optimize or nearly optimize both simplicity and precision. The labels applied to kin are constructed from simple units and are precise enough to reduce confusion and ambiguity when used in communication. <jats:bold>Frank and Goodman</jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="998" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1218633">998</jats:related-article> ) show that simplicity and precision also explain how listeners correctly infer the meaning of speech in the context of referential communication. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 998-998

Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila Dorsal-Ventral Axis

Tongtong Zhao; Owen S. Graham; Alexandre Raposo; Daniel St Johnston

<jats:title>Pull Me-No!-Push You</jats:title> <jats:p> The <jats:italic>Drosophila</jats:italic> dorsal-ventral (DV) axis is polarized by the movement of the nucleus from the posterior end of the oocyte to its anterior margin. It has long been assumed that the nucleus is pulled to the anterior end by the molecular motor dynein along the polarized microtubule cytoskeleton that defines the anterior-posterior (AP) axis. Using live imaging, <jats:bold> Zhao <jats:italic>et al.</jats:italic> </jats:bold> (p. 999, published online 12 April; see the Perspective by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6084" page="984" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1223141"> <jats:bold>Bowerman and O'Rourke</jats:bold> </jats:related-article> ) now demonstrate that the nucleus is pushed toward the anterior by the force exerted by growing microtubules hitting its posterior side. DV polarity thus depends on the posterior positioning of the microtubule organizing center rather than on AP axis formation. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 999-1003