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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Where Is PTEN?

Nicholas R. Leslie; Valerie G. Brunton

<jats:p> A tumor suppressor protein may function in multiple locations inside and outside the originating cell. <jats:named-content content-type="related-content"> [Also see Reports by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="395" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1236188"> Bassi <jats:italic>et al.</jats:italic> </jats:related-article> and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="399" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1234907"> Hopkins <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 355-356

A Path to Complex Carbohydrates

Laura L. Kiessling; Matthew B. Kraft

<jats:p> A general strategy for synthesizing asymmetrically branched carbohydrates will help to elucidate their biological functions. <jats:named-content content-type="related-content"> [Also see Report by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="379" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1236231"> Wang <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 357-358

Genome Mosaicism—One Human, Multiple Genomes

James R. Lupski

<jats:p>The cells in our body do not all contain identical genomes, which has implications for health and disease.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 358-359

Engaging High School Students in Research on Smoking Behavior

Maureen M. Munn; Hiroki Oura; Mark Gallivan; Katie Van Horne; Andrew W. Shouse

<jats:p>Exploring Databases, an IBI prize–winning module, enables students to conduct epidemiological research on smoking behavior using a database.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 360-361

AAAS News and Notes

<jats:p> A monthly roundup of recent news and projects of <jats:italic>Science</jats:italic> 's publisher, the American Association for the Advancement of Science. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 362-362

I-Love-Q: Unexpected Universal Relations for Neutron Stars and Quark Stars

Kent Yagi; Nicolás Yunes

<jats:title>Neutron Star Measurements</jats:title> <jats:p> Neutron stars are one of the densest manifestations of matter in the universe. <jats:bold>Yagi and Yunes</jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="365" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1236462">365</jats:related-article> ) examined the moment of inertia of neutron stars, which determines how fast they can spin, and the quadrupole moment and tidal Love number, which determine how much they can be deformed. The findings suggest that these three quantities obey universal relationships that are independent of the internal structure of the stars, implying that measurements of one of the three could accurately predict the other two. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 365-368

Holographic Vortex Liquids and Superfluid Turbulence

Paul M. Chesler; Hong Liu; Allan Adams

<jats:title>Holographic Turbulence</jats:title> <jats:p> Turbulence in a superfluid presents an even more challenging theoretical problem than classical turbulence. <jats:bold> Chesler <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="368" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1233529">368</jats:related-article> ) studied simulated superfluid turbulence using holographic duality. The direction of the energy flow in a two-dimensional superfluid was opposite to that in classical fluids—the energy injected at long length scales dissipated at short length scales through the vortices that form in a turbulent superfluid. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 368-372

Element-Resolved Corrosion Analysis of Stainless-Type Glass-Forming Steels

M. J. Duarte; J. Klemm; S. O. Klemm; K. J. J. Mayrhofer; M. Stratmann; S. Borodin; A. H. Romero; M. Madinehei; D. Crespo; J. Serrano; S. S. A. Gerstl; P. P. Choi; D. Raabe; F. U. Renner

<jats:title>Rust Resistance</jats:title> <jats:p> The rusting of iron and steel can be prevented through the addition of 11% or more chromium. The addition of molybdenum can enhance the corrosion resistance, with a complex interplay between the Cr and Mo atoms. However, if chemical variations exist, corrosion can still occur in localized regions or if the surface layer is mechanically abraded. <jats:bold> Duarte <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="372" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1230081">372</jats:related-article> ) studied the corrosive failure of an iron-based glassy alloy. A combination of atom probe tomography, electron microscopy, and x-ray diffraction was used to build up a near atomistic picture of local variations in the metal as it was heated and allowed to crystallize, and the impact these processes have on the corrosion resistance. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 372-376

Geometric Frustration of Icosahedron in Metallic Glasses

A. Hirata; L. J. Kang; T. Fujita; B. Klumov; K. Matsue; M. Kotani; A. R. Yavari; M. W. Chen

<jats:title>Order, Order</jats:title> <jats:p> The structure of glassy materials, which are known to have short-range order but no long-range pattern, continues to be a puzzle. One current theory is that some glassy materials possess icosahedral ordering, a motif that cannot show translational periodicity. <jats:bold> Hirata <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="376" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1232450">376</jats:related-article> , published online 11 July) obtained diffraction patterns from subnanometer volumes in a metallic glass, which show some, but not all, of the expected features of an icosahedron. Simulations suggest that the patterns arise from icosahedrons distorted to include features of the face-centered cubic structure. This observation is different from the predictions of molecular dynamics simulations and provides pivotal information in understanding the competition between the formation of the globally inexpensive long-range order and the locally inexpensive short-range order. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 376-379

A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N -Glycans

Zhen Wang; Zoeisha S. Chinoy; Shailesh G. Ambre; Wenjie Peng; Ryan McBride; Robert P. de Vries; John Glushka; James C. Paulson; Geert-Jan Boons

<jats:title>Sweet Variety</jats:title> <jats:p> Proteins fold into a great variety of shapes—but, topologically, they always start as a more or less straight line of linked amino acids. In contrast, carbohydrates manifest a range of structures in which the sugar building blocks connect through multiple branch points. <jats:bold> Wang <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="379" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1236231">379</jats:related-article> , published online 26 July; see the Perspective by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6144" page="357" related-article-type="in-this-issue" vol="341" xlink:href="10.1126/science.1241788"> <jats:bold>Kiessling and Kraft</jats:bold> </jats:related-article> ) designed a versatile precursor that could be transformed into many different branched glycans with distinct building blocks along each branch. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 379-383