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Institución detectada	Período	Navegá	Descargá	Solicitá
No detectada	desde mar. 1997 / hasta dic. 2023	Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

1880-

Cobertura temática

Ciencias naturales

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doi: 10.1126/science.1242454

Fueling Immunity: Insights into Metabolism and Lymphocyte Function

Erika L. Pearce; Maya C. Poffenberger; Chih-Hao Chang; Russell G. Jones

<jats:title>Lymphocyte Metabolism</jats:title> <jats:p> Lymphocytes are highly dynamic cells, undergoing extensive proliferation upon infection and then reducing in number upon pathogen clearance. Lymphocytes also circulate through many different tissue environments that vary in their nutrient and oxygen availability. Recent studies have revealed changes in metabolic programming that facilitate this dynamic behavior. How these changes occur and the specific effects that they have on lymphocyte function and on the ultimate outcome of an infection are not well understood. <jats:bold> Pearce <jats:italic>et al.</jats:italic> </jats:bold> ( <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.sciencemag.org/content/342/6155/1242454.full">1242454</jats:ext-link> ) review recent progress in this area, suggest how parallels might be found in studying the metabolic changes seen in tumor cells, and propose challenges for the future. </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

doi: 10.1126/science.342.6155.159-i