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Institución detectada	Período	Navegá	Descargá	Solicitá
No detectada	desde mar. 1997 / hasta dic. 2023	Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

1880-

Cobertura temática

Ciencias naturales

Tabla de contenidos

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doi: 10.1126/science.1253344

Breast Cancerâ€”Thinking Globally

Benjamin O. Anderson

<jats:p> Few diseases have seen more rapid scientific progress over the past three decades than breast cancer. Beginning in the 1980s, screening mammography led to sweeping improvements in early cancer detection. At the same time, endocrine treatment and systemic chemotherapy proved life-saving. The development of drugs that target hormone receptor and <jats:italic>HER2/neu</jats:italic> oncogene signaling pathways, coupled with biomarker-based subclassification of the disease, have helped make breast cancer therapy a more precise science. Cloning of the <jats:italic>BRCA</jats:italic> genes provided insight into inherited predisposition and the opportunity for genetic testing. As a result of these advances, breast cancer death rates in the United States dropped by 34% between 1990 and 2014. </jats:p>