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<jats:p> A better inventory of lunar volatiles will help improve our understanding of the origin and evolution of the Earth-Moon system. <jats:named-content content-type="related-content"> [Also see Report by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="400" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1250398"> Boyce <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p> Single-cell sequencing reveals the microdiversity of the most abundant photosynthetic organism on Earth. <jats:named-content content-type="related-content"> [Also see Report by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="416" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1248575"> Kashtan <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p> A synthetic route photoactivates one reactant and then controls stereochemistry of subsequent steps to form a single isomer of a four-membered ring. <jats:named-content content-type="related-content"> [Also see Report by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="392" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1251511"> Du <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p> Engineered channelrhodopsins conduct anions rather than cations, changing the action potential of neurons. <jats:named-content content-type="related-content"> [Also see Reports by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="409" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1249375"> Wietek <jats:italic>et al.</jats:italic> </jats:related-article> and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="420" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1252367"> Berndt <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p> Do alternating stacking modes of nucleosomes underlie the compaction of chromatin? <jats:named-content content-type="related-content"> [Also see Research Article by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="376" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1251413"> Song <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p> A combination of technologies reveals which neurons constitute circuits for specific behaviors in <jats:italic>Drosophila</jats:italic> larvae. <jats:named-content content-type="related-content"> [Also see Research Article by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="386" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1250298"> Vogelstein <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p>Field projects are beginning to demonstrate the potential for carbon storage in basaltic rocks.</jats:p>

<jats:p> A monthly roundup of recent news and projects of <jats:italic>Science</jats:italic> 's publisher, the American Association for the Advancement of Science. </jats:p>

<jats:title>Double Helix, Doubled</jats:title> <jats:p> Chromatin consists of genomic DNA packaged onto nucleosomes—double donut-shaped complexes of histone proteins. Roughly 150 base pairs of DNA are wrapped around each nucleosome with variable lengths of linker DNA in-between. Using cryogenic electron microscopy, <jats:bold> Song <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="376" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1251413">376</jats:related-article> ; see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="370" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1253852">Travers</jats:related-article> </jats:bold> ) determined the 11 angstrom–resolution structure of a 12-nucleosome string of DNA. The segment forms a 30-nanometer fiber structure, which is itself double-helical, like the DNA it packages. </jats:p>

<jats:title>Africa's Bane</jats:title> <jats:p> Tsetse are blood-feeding, fast-flying flies that transmit a range of <jats:italic>Trypanosoma</jats:italic> spp. protozoan pathogens, which cause sleeping sickness in humans and their nagana in their livestock. The <jats:bold> International <jats:italic>Glossina</jats:italic> Genome Initiative </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6182" page="380" related-article-type="in-this-issue" vol="344" xlink:href="10.1126/science.1249656">380</jats:related-article> ) sequenced the genome of <jats:italic>Glossina morsitans</jats:italic> and identified the genes for many attributes of the tsetse's remarkable biology, including viviparity and the expression of analogs of mammalian milk proteins. Tsetse are host to several specific symbionts that appear to synthesize essential nutrients for the fly and also to hitherto undiscovered parasitoid-derived viruses. Deeper exploration of this genome will reveal what makes these fly species so host- and trypanosome specific. </jats:p>