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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Niche engineering demonstrates a latent capacity for fungal-algal mutualism

Erik F. Y. Hom; Andrew W. Murray

<jats:title>It takes two to tango in restricted environments</jats:title> <jats:p> Despite being unrelated, freeliving algae and fungi can learn to help one another out. Hom and Murray raised the green alga <jats:italic>Chlamydomonas reinhardtii</jats:italic> in CO <jats:sub>2</jats:sub> -restricted environments in the presence of the yeast <jats:italic>Saccharomyces cerevisiae</jats:italic> (see the Perspective by Aanen and Bisseling). The experimental setup forced the two species to depend on one another for the metabolic production of CO <jats:sub>2</jats:sub> , which is provided by the yeast as it consumes glucose and is needed by the alga, and ammonia, which conversely can be made from nitrite by the alga and then used by the yeast. This dependence was seen under a broad range of environmental conditions. Similar tests between other <jats:italic>Chlamydomonas</jats:italic> and fungal species revealed the ability to create a phylogenetically broad range of mutualisms. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6192" page="94" related-article-type="in-this-issue" vol="345" xlink:href="10.1126/science.1253320">94</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6192" page="29" related-article-type="in-this-issue" vol="345" xlink:href="10.1126/science.1256542">29</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 94-98

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

Min Lu; David A. Lawrence; Scot Marsters; Diego Acosta-Alvear; Philipp Kimmig; Aaron S. Mendez; Adrienne W. Paton; James C. Paton; Peter Walter; Avi Ashkenazi

<jats:title>Life and death and quality control</jats:title> <jats:p> When cells are subjected to too much stress, they curl up their toes and die. Lu <jats:italic>et al.</jats:italic> describe a clever strategy cells use to stay alive as long as they are not stressed for too long. The cells' quality-control machinery will activate a so-called death receptor when defective proteins accumulate within the cell, a sign of stress—but they will wait until the proteins have built up for a good long time. If stress is relieved soon enough, levels of the death receptor decay back to normal, and the cells stay alive; otherwise, R.I.P. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6192" page="98" related-article-type="in-this-issue" vol="345" xlink:href="10.1126/science.1254312">98</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 98-101

New Products

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 102-102

Science Podcast: 4 July Show

<jats:p>On this week's show: Psychedelic resurgence and a roundup of stories from our daily news site.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 102-102

A giant leap

John N. (Jack) Kittinger

Palabras clave: Multidisciplinary.

Pp. 110-110

Selection bias at the heterosexual HIV-1 transmission bottleneck

Jonathan M. Carlson; Malinda Schaefer; Daniela C. Monaco; Rebecca Batorsky; Daniel T. Claiborne; Jessica Prince; Martin J. Deymier; Zachary S. Ende; Nichole R. Klatt; Charles E. DeZiel; Tien-Ho Lin; Jian Peng; Aaron M. Seese; Roger Shapiro; John Frater; Thumbi Ndung’u; Jianming Tang; Paul Goepfert; Jill Gilmour; Matt A. Price; William Kilembe; David Heckerman; Philip J. R. Goulder; Todd M. Allen; Susan Allen; Eric Hunter

<jats:title>HIV needs to be fit to transmit</jats:title> <jats:p> Although you might not think it, it's hard to catch HIV. Less than 1% of unprotected sexual exposures result in infection. What then leads to transmission? Carlson <jats:italic>et al.</jats:italic> determined the amino acid sequence of viruses infecting 137 Zambian heterosexual couples in which one partner infected the other (see the Perspective by Joseph and Swanstrom). The authors then used statistical modeling and found that transmitted viruses are typically the most evolutionarily fit. That is, compared to other viral variants in the infected person, the transmitted virus most closely matches the most common viral sequence found in the Zambian population. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.1254031">10.1126/science.1254031</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6193" page="136" related-article-type="in-this-issue" vol="345" xlink:href="10.1126/science.1257425">136</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

For HIV: Location, location, location

K. L. Mueller

Palabras clave: Multidisciplinary.

Pp. i-176

A focus on child development

Karlee L. Silver; Peter A. Singer

<jats:p>By September 2014, the United Nations (UN) Open Working Group will present its final report on the Sustainable Development Goals to the UN Secretary General and President of the General Assembly, who will finalize these goals by September 2015. Because these goals (the successors to the Millennium Development Goals) will guide global action through 2030, it is unfortunate that early child development is not yet effectively addressed in this framework. Investing in child development is the foundation for improved health, economic, and social outcomes. Not getting the early years “right” is linked to violent behavior, depression, higher rates of noncommunicable disease, and lower wages, and it negatively affects a nation's gross domestic product. Unless early child development is addressed effectively in the UN Sustainable Development Goals, countries will be locked into poverty, and sustainable development will not be achieved.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 121-121

This week's section

<jats:p>A roundup of weekly science policy and related news.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 122-124

Uncontacted tribe in Brazil emerges from isolation

Heather Pringle

<jats:p>Anthropologists worry about the threat from novel infections and conflicts with other tribes.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 125-126