Catálogo de publicaciones - revistas

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

<jats:p> Characterization of therapeutic proteins remains labor-intensive and time consuming due to their often complex and heterogeneous structure. This has led to a concerted effort within the biotechnology and biopharmaceutical industry to address these bottlenecks as a means to boost the development of more biotherapeutics. Studies in this vein, such as testing the effect of various cell culture conditions on posttranslational modifications or monitoring the purification process of recombinant proteins, produce large numbers of samples that can easily exceed the capacity of modern analytical laboratories. High throughput analytical platforms with high precision, automation, and ease-of-use are therefore in great demand. To this end, the use of microfluidic analytical platforms such as microchip capillary electrophoresis (CE) have greatly increased the efficiency and reproducibility needed for analyzing proteins intended for therapeutic use. In this webinar, our expert panelists will discuss posttranslational modifications and quality assessment of biotherapeutic proteins for biopharmaceutical development using microfluidic-CE characterization. <jats:list list-type="bullet"> <jats:list-item> <jats:p> <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://webinar.sciencemag.org/webinar/archive/improving-characterization-monoclonal-antibodies">View the Webinar</jats:ext-link> </jats:p> </jats:list-item> </jats:list> </jats:p>

<jats:p>On this week's show: Hippos' contribution to the environment and a news roundup.</jats:p>

<jats:p> The science of the very small is big business these days, as nanotechnology becomes a huge part of multiple sectors. In particular, scientists, engineers, and clinicians who endeavor to better understand how nanotechnology can impact biological systems—through the use of biosensors, biopharmaceuticals, and biomaterials—are finding abundant opportunities to pursue these investigations in multiple environments. Across the globe, demand is high in biosystems nanotechnology for professionals who speak the language of engineering and biology and have skill sets that include collaborating on diverse teams. <jats:list list-type="bullet"> <jats:list-item> <jats:p> <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2014_11_14/science.opms.r1400149">Read the Feature (Full-Text HTML)</jats:ext-link> </jats:p> </jats:list-item> <jats:list-item> <jats:p> <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://sciencecareers.sciencemag.org/sites/default/files/14%2520Nov%2520Nanotech%2520Feature.pdf">Read the Feature (PDF)</jats:ext-link> </jats:p> </jats:list-item> </jats:list> </jats:p>

<jats:p> About a year ago, Bruce Alberts and I announced the launch of <jats:italic>Science</jats:italic> in the Classroom ( <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://scienceintheclassroom.org">scienceintheclassroom.org</jats:ext-link> ), an online resource of annotated research papers published in <jats:italic>Science</jats:italic> , with associated teaching materials designed to help pre-college and college students understand how science moves forward as a structured way of revealing the laws of nature. Since its fledgling beginning last year, the project has expanded its subject diversity and continues to add articles at the rate of two per month. These articles have reached about 3000 users per month. But now it is time to take this project to the next level—and you can help, by annotating new papers and designing creative activities to accompany them. </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Elation and disappointment as lander goes into early hibernation, curtailing experiments.</jats:p>