Catálogo de publicaciones - revistas

<jats:title>Fibroblasts in fibrosis</jats:title> <jats:p> Excess fibrous connective tissue, similar to scarring, forms during the repair of injuries. Fibroblasts are known to be involved, but their role is poorly characterized. Rinkevich <jats:italic>et al.</jats:italic> identify two lineages of dermal fibroblasts in the dorsal skin of mice (see the Perspective by Sennett and Rendl). A fibrogenic lineage, defined by embryonic expression of <jats:italic>Engrailed-1</jats:italic> , plays a central role in dermal development, wound healing, radiation-induced fibrosis, and cancer stroma formation. Targeted inhibition of this lineage results in reduced melanoma growth and scar formation, with no effect on the structural integrity of the healed skin, thus indicating therapeutic approaches for treating fibrotic disease. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaa2151">10.1126/science.aaa2151</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6232" page="284" related-article-type="in-this-issue" vol="348" xlink:href="10.1126/science.aab0120">284</jats:related-article> </jats:p>

<jats:title>Similar shapes inhabit the sea</jats:title> <jats:p>Over biological history, several different groups of vertebrate tetrapods have reinvaded the marine environment. Although these groups are widely distributed among reptiles, mammals, amphibians, and birds, the shapes they have evolved are remarkably similar. Kelley and Pyenson review the literature on marine vertebrate groups over time and describe the innovations that facilitated the evolution of these marine forms, the environmental conditions that selected for such convergence of form, and the threats they face from future environment change.</jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaa3716">10.1126/science.aaa3716</jats:related-article> </jats:p>

<jats:p>This month, the United States takes over the chairmanship of the Arctic Council, a position it last held in 1998. Since then, global interest in the Arctic has increased, and the council has evolved considerably. What has spurred that interest, and what will the council focus on under U.S. leadership?</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Without snowmelt, streams in the western U.S. could reach lethal temperatures.</jats:p>

<jats:p>Female candidates twice as likely to get top rating.</jats:p>