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Science
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells
Georg Stary; Andrew Olive; Aleksandar F. Radovic-Moreno; David Gondek; David Alvarez; Pamela A. Basto; Mario Perro; Vladimir D. Vrbanac; Andrew M. Tager; Jinjun Shi; Jeremy A. Yethon; Omid C. Farokhzad; Robert Langer; Michael N. Starnbach; Ulrich H. von Andrian
<jats:title>The right combination for protection</jats:title> <jats:p> Despite its prevalence, no vaccine exists to protect against infection with the sexually transmitted bacterium <jats:italic>Chlamydia trachomatis</jats:italic> . Stary <jats:italic>et al.</jats:italic> now report on one potential vaccine candidate (see the Perspective by Brunham). Vaccinating with an ultraviolet light-inactivated <jats:italic>C. trachomatis</jats:italic> linked to adjuvant-containing charged nanoparticles protected female conventional and humanized mice against <jats:italic>C. trachomatis</jats:italic> infection. The vaccine conferred protection only when delivered through mucosal routes. Protection relied on targeting the bacteria to a particular population of immunogenic dendritic cells and inducing memory T cells that resided in the female genital tract. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaa8205">10.1126/science.aaa8205</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6241" page="1322" related-article-type="in-this-issue" vol="348" xlink:href="10.1126/science.aac6528">1322</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible
Composite membranes for filtering solvents
M. S. Lavine
Palabras clave: Multidisciplinary.
Pp. i-1327
Parks for science
Gary Machlis; Marcia McNutt
<jats:p>In March 1915, a historic conference of scientists, conservationists, and park leaders was held at the University of California, Berkeley. It helped create public support for national parks in the United States and the establishment in 1916 of the National Park Service (NPS). One hundred years later, a similar summit on the same Berkeley campus convened to examine the role of science in the next century of America's national parks. Science remains crucial to the future health of America's parks and protected areas worldwide. But national parks are also vital for science.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1291-1291
This week's section
<jats:p>A roundup of weekly science policy and related news.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1292-1294
The return of Philae
Eric Hand; Daniel Clery
<jats:p>Revived after hibernation, comet lander awaits orders.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1295-1295
Research chimps will soon be listed as ‘endangered’
David Grimm
<jats:p>Ruling could disrupt biomedical research.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1296-1296
Designer proteins produce potent HIV defense
Jon Cohen
<jats:p>AIDS vaccine developers mimic natural route to powerful immune responses.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1297-1297
Republicans split on climate, social science spending
Jeffrey Mervis
<jats:p>House calls for cuts, Senate favors status quo.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1298-1298
Pumped up to rumble
Julia Rosen
<jats:p>Massive studies of wastewater injection wells show fast pumping raises earthquake risk.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1299-1299
Last dance?
Marianne Lavelle
<jats:p>An urgent effort to save the West's iconic lesser prairie chicken could point the way to a truce in other endangered-species battles.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1300-1305