Catálogo de publicaciones - revistas

<jats:title>Microbiota can mislead antibodies</jats:title> <jats:p> Unlike the response to many viral infections, most people do not produce antibodies capable of clearing HIV-1. Non-neutralizing antibodies that target HIV-1's envelope glycoprotein (Env) typically dominate the response, which is generated by B cells that cross-react with Env and the intestinal microbiota. Williams <jats:italic>et al.</jats:italic> analyzed samples from individuals who had received a vaccine containing the Env protein, including the gp41 subunit. Most of the antibodies were non-neutralizing and targeted gp41. The antibodies also reacted to intestinal microbiota, suggesting that preexisting immunity to microbial communities skews vaccineinduced immune responses toward an unproductive target. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aab1253">10.1126/science.aab1253</jats:related-article> . </jats:p>

<jats:title>Improving transistors with nanomaterials</jats:title> <jats:p>High-performance silicon transistors and thin-film transistors used in display technologies are fundamentally limited to miniaturization. Incorporating nanomaterials—such as carbon nanotubes, graphene, and related two-dimensional materials like molybdenum disulfide—into these devices as gate materials may circumvent some of these limitations. Franklin reviews the opportunities and challenges for incorporating nanomaterials into transistors to improve performance. Because high-performance transistors are distinct from thin-film transistors, incorporating them into flexible or transparent platforms raises new challenges.</jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aab2750">10.1126/science.aab2750</jats:related-article> </jats:p>

<jats:p> After years of public leadership around fairness, equity, and diversity in science and engineering, the American Association for the Advancement of Science (AAAS) and its journal <jats:italic>Science</jats:italic> recently have been questioned about this leadership. AAAS is, after all, the organization that stopped all annual meetings in the “Jim Crow” South in the 1950s; that, at great expense, pulled its meeting out of Chicago to respect the ban on meeting in states that did not ratify the Equal Rights Amendment (1979); that held the first fully accessible professional meeting in Boston (1976), long before passage of the Americans with Disabilities Act; and that, in 1972, established the Committee on Opportunities in Science to advise what is now a mostly female AAAS Board of Directors on diversity issues. Long before public support of the rights of LGBTQ individuals, AAAS passed a nondiscrimination resolution (1975). The values upon which this organization is based not only remain intact, but continue to strengthen through dialogues with the scientific community and through actions that advance science for the benefit of all. </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>