Catálogo de publicaciones - revistas

<jats:title>Duplications and deletions in the human genome</jats:title> <jats:p> Duplications and deletions can lead to variation in copy number for genes and genomic loci among humans. Such variants can reveal evolutionary patterns and have implications for human health. Sudmant <jats:italic>et al.</jats:italic> examined copy-number variation across 236 individual genomes from 125 human populations. Deletions were under more selection, whereas duplications showed more population-specific structure. Interestingly, Oceanic populations retain large duplications postulated to have originated in an ancient Denisovan lineage. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aab3761">10.1126/science.aab3761</jats:related-article> </jats:p>

<jats:p> This week, Puerto Rico hosts scientists and other stakeholders in Caribbean science to discuss “Attaining Sustainability Through Science and Education.” <jats:xref ref-type="fn">*</jats:xref> This comes at the end of a summer that saw the island's economy “death spiral” into a first-ever default on a bond payment. Its more than $70 billion in debt, high unemployment, and a shrinking economy are causing Puerto Ricans to leave the island in droves in search of stability. This includes young scientists and biomedical professionals. Austerity measures being considered by the Puerto Rican government include reducing support for higher education, but this would only drive the brain drain, decimate the scientific enterprise, and reduce the capacity to confront the economic and environmental challenges: a perfect storm that would be devastating to Puerto Rico's future. Robust science and technology are needed now more than ever to avoid this catastrophe. </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Bizarre skeletons emerge from South African cave.</jats:p>

<jats:p>Promise of cancer-seeking nanoparticles wins funding for research center.</jats:p>

<jats:p>In Alaska, frozen debris lobes threaten a key lifeline.</jats:p>

<jats:p>A new viral “backbone” could speed up production of influenza vaccines.</jats:p>

<jats:p>As head of the $29 billion Wellcome Trust, Jeremy Farrar took the stage during the Ebola epidemic. Now, he wants to make the trust a world leader.</jats:p>

<jats:p>Researchers are vying to use renewable energy to suck carbon dioxide out of the air and turn it back into fuel.</jats:p>