Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Popular gene-editing technique gets sharper molecular scissors
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
Light-based memory chip is first to permanently store data
Robert Service
Palabras clave: Multidisciplinary.
Pp. No disponible
Synthetic biology’s clinical applications
Mike May
Palabras clave: Multidisciplinary.
Pp. No disponible
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
Chanhee Kang; Qikai Xu; Timothy D. Martin; Mamie Z. Li; Marco Demaria; Liviu Aron; Tao Lu; Bruce A. Yankner; Judith Campisi; Stephen J. Elledge
<jats:title>Transcriptional control of cell senescence</jats:title> <jats:p> Senescent cells that have stopped proliferating secrete molecules that influence the cells around them. Prevention of this senescence-activated secretory phenotype seems to slow organismal aging. Kang <jats:italic>et al.</jats:italic> explored the regulatory process behind cell senescence and found that DNA damage led to stabilization of the transcription factor GATA4 (see the Perspective by Cassidy and Narita). Increased activity of GATA4 in senescent cells stimulated genes encoding secreted factors. GATA4 also accumulates in the brains of aging mice or humans. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaa5612">10.1126/science.aaa5612</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6255" page="1448" related-article-type="in-this-issue" vol="349" xlink:href="10.1126/science.aad2501">1448</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible
Therapeutic opportunity knocks
A. Colmone
Palabras clave: Multidisciplinary.
Pp. i-1501
Preimplantation genetic screens
Arthur L. Beaudet
<jats:p>Although our knowledge of genetic abnormalities that cause health disorders is expanding, the pace of discovering cures for genetic diseases is not nearly as fast. However, technologies applicable to preventing heritable genetic diseases have been developing, among them so-called “next-generation sequencing.” This efficient and inexpensive means to sequence DNA has revolutionized the study of genomics and could play a major role in future preimplantation genetic screening approaches. It may even improve screening during early pregnancy.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1423-1423
This week's section
<jats:p>A roundup of weekly science policy and related news.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1426-1428
Sleuthing sheds light on STAP cell fiasco
Gretchen Vogel
<jats:p>Researchers describe artifacts that could have misled authors and prompted sensational reprogramming claims.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1430-1431
How teeth got tough: enamel's evolutionary journey
Sid Perkins
<jats:p>Fossils show that ancient fish scales sported enamel long before this hard substance coated teeth.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1431-1431
The Martian's ode to science
Meghna Sachdev
<jats:p>The director, author, and a NASA expert on how they balanced realism and movie magic.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1432-1432