Catálogo de publicaciones - revistas

<jats:title>Getting a handle on a cross-linking motif</jats:title> <jats:p> Although protein backbones consist exclusively of amino acids, various other molecules in the cell often get latched on afterward in a process termed posttranslational modification. In one such motif, called glucosepane, the side chains of lysine and arginine form a condensed cross-link through a reaction sequence with glucose. Formation of this cross-link is of interest in diabetes research. Draghici <jats:italic>et al.</jats:italic> now report a chemical synthesis of glucosepane outside the broader environment of a surrounding protein (see the Perspective by Boger). This synthesis should facilitate more precise characterization of the structure and function of the motif in vivo. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="294" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aac9655">294</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="275" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad3298">275</jats:related-article> </jats:p>

<jats:title>A direct route from acids to alcohols</jats:title> <jats:p> Making alcohols via hydrogen addition to C=O bonds is among the most widely applied reactions in chemistry. The transformation has also garnered renewed interest for generating commodity chemicals from biomass. Korstanje <jats:italic>et al.</jats:italic> now show that a cobalt compound can catalyze hydrogenation of the C=O bonds in carboxylic acids. These constitute a particularly challenging substrate class, given the propensity of many other catalysts to degrade under acidic conditions. The cobalt catalyst tolerates a versatile substrate range, and the Earth abundance of the metal bodes well for long-term utility. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="298" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aaa8938">298</jats:related-article> </jats:p>

<jats:title> Grabbing CO <jats:sub>2</jats:sub> from wet gas streams </jats:title> <jats:p> It is a challenge to extract CO <jats:sub>2</jats:sub> from typical gas streams, such as the flue gas from a power plant. This is because any water in the stream tends to prevent CO <jats:sub>2</jats:sub> absorption and may also degrade the absorbing material. Datta <jats:italic>et al.</jats:italic> developed a microporous copper silicate that avoids these problems. Most other materials have sites that absorb both water and CO <jats:sub>2</jats:sub> at the same sites, and in that fight, the water tends to win. Although their material still absorbs water, it has separate sites for the CO <jats:sub>2</jats:sub> absorption. It also shows good stability despite the absorbed water and can be reused. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="302" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aab1680">302</jats:related-article> </jats:p>

<jats:title>Stringing together a powerful amplifier</jats:title> <jats:p> Amplifying microwave signals with high gain and across a broad range of frequencies is crucial in solid-state quantum information processing (QIP). Achieving broadband operation is especially tricky. Macklin <jats:italic>et al.</jats:italic> engineered an amplifier that contains a long chain of so-called Josephson junctions (see the Perspective by Cleland). The amplifier exhibited high gain over a gigahertz-sized bandwidth and was able to perform high-fidelity qubit readout. Because the amplifier will be capable of reading out as many as 20 qubits simultaneously, it may help to scale up QIP protocols. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="307" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aaa8525">307</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="280" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad0858">280</jats:related-article> </jats:p>

<jats:title>Understanding abyssal hill spacing</jats:title> <jats:p> The most prominent topographic features on Earth are abyssal hills found on the bottom of the ocean floor. Olive <jats:italic>et al.</jats:italic> wanted to understand the spacing and size of these hills. They used a model that combines magma supply and the mechanical response of the crust. The model explains observations of hill spacing around mid-ocean ridges. Crustal topography appears to be a poor recorder of changes in magma supply. However, magma supply changes may be faithfully recorded at the base of the crust. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="310" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad0715">310</jats:related-article> </jats:p>

<jats:title>Sensing the force digitally</jats:title> <jats:p> Our skin provides us with a flexible waterproof barrier, but it also contains a sensor array that feels the world around us. This array provides feedback and helps us to avoid a hot object or increase the strength of our grip on an object that may be slipping away. Tee <jats:italic>et al.</jats:italic> describe an approach to simulate the mechanoreceptors of human skin, using pressure-sensitive foils and printed ring oscillators (see the Perspective by Anikeeva and Koppes). The sensor successfully converted pressure into a digital response in a pressure range comparable to that found in a human grip. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="313" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aaa9306">313</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="274" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad0910">274</jats:related-article> </jats:p>

<jats:title>Changes over time build neuronal diversity</jats:title> <jats:p> Although neural progenitors can keep generating new neurons, they can generate different neurons as the organism develops. Two different sections of the <jats:italic>Drosophila</jats:italic> brain, the mushroom bodies and the antennal lobes, show this characteristic, although the antennal lobes produce more different types of neurons over development than do the mushroom bodies. Liu <jats:italic>et al.</jats:italic> identified two RNA-binding proteins that manage this change over development in both settings. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="317" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad1886">317</jats:related-article> </jats:p>

<jats:title>Ocean circulation changes not needed</jats:title> <jats:p> What causes the pattern of sea surface temperature change that is seen in the North Atlantic Ocean? This naturally occurring quasi-cyclical variation, known as the Atlantic Multidecadal Oscillation (AMO), affects weather and climate. Some have suggested that the AMO is a consequence of variable large-scale ocean circulation. Clement <jats:italic>et al.</jats:italic> suggest otherwise. They find that the pattern of AMO variability can be produced in a model that does not include ocean circulation changes, but only the effects of changes in air temperatures and winds. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6258" page="320" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aab3980">320</jats:related-article> </jats:p>