Catálogo de publicaciones - revistas

<jats:title>HIV proteins exploit clathrin coats</jats:title> <jats:p> Clathrin-coated vesicles are involved in the sorting of membrane and cargo at the trans-Golgi network. Clathrin coats exploit adaptor proteins, including AP-1 and AP-2, in selecting their cargoes, assisted by the small membrane-trafficking associated GTPase Arf1. Shen <jats:italic>et al.</jats:italic> were interested in how the HIV-1 Nef protein affected this process. They leveraged a structure solved in the presence of Nef to show that the AP-1:clathrin coat is far more intricately organized than previously thought. Furthermore, Arf1 played a central structural role in these coated vesicles. It seems that HIV-1 Nef hijacks the clathrin pathway to its own ends through very sophisticated structural perturbations. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aac5137">10.1126/science.aac5137</jats:related-article> </jats:p>

<jats:p>Last month in New York, the world adopted the Sustainable Development Goals (SDGs), defining the global development agenda for the next 15 years. Among the 17 goals is Goal 7's aim to ensure “access to affordable, reliable, sustainable and modern energy for all.” Given that an estimated 1.3 billion people have no access to electricity and that 70% of the world's poor live off-grid in the countryside, this is indeed ambitious. How do we ensure that these remote communities have access to energy?</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Search for rare nuclear decay would test whether the neutrino is its own antiparticle.</jats:p>

<jats:p>Astronomer Joan Schmelz talks about what needs to change in the wake of the Marcy case.</jats:p>

<jats:p>Workshop explores facilities to give neuroscience access to high-tech tools.</jats:p>

<jats:p>Cellular droplets promote vital biochemistry—but may dangerously solidify</jats:p>

<jats:p>Industry uneasy at European Food Safety Authority pledge to make data underlying its decisions public.</jats:p>

<jats:p>Germany completes the epic construction of the reactor designed in hell. Its tortuous shape may point the way forward for fusion.</jats:p>