Catálogo de publicaciones - revistas

<jats:title>Generations affected by histone changes</jats:title> <jats:p> Parent and even grandparent environmental exposure can transmit adverse health effects to offspring. The mechanism of transmission is unclear, but some studies have implicated variations in DNA methylation. In a mouse model, Siklenka <jats:italic>et al.</jats:italic> found that alterations in histone methylation during sperm formation in one generation leads to reduced survival and developmental abnormalities in three subsequent generations (see the Perspective by McCarrey). Although changes in DNA methylation were not observed, altered sperm RNA content and abnormal gene expression in offspring were measured. Thus, chromatin may act as a mediator of molecular memory in transgenerational inheritance. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aab2006">10.1126/science.aab2006</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6261" page="634" related-article-type="in-this-issue" vol="350" xlink:href="10.1126/science.aad5138">634</jats:related-article> </jats:p>

<jats:p>On 20 September 2015, the Global Commission for the Certification of Poliomyelitis Eradication (GCC) declared that type 2 wild poliovirus had been eradicated. The GCC examined reports from 189 of 195 countries around the world and studied separate data [held by the World Health Organization (WHO)] from the remaining countries. According to WHO, nearly 2 million appropriate clinical samples had been tested, and no type 2 wild polioviruses were found. The announcement is the first step toward eradicating all three wild poliovirus types. But this landmark will only be declared when the GCC is confident that there have been no wild virus cases of any type for 3 years.</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>A new picture of water in the deep Earth predicts surprising chemistry.</jats:p>

<jats:p>Gut bacteria boost immunotherapies.</jats:p>

<jats:p>The new 2-year U.S. budget deal is frontloaded, with most of the spending increase coming in 2016.</jats:p>

<jats:p>Programs to yoke mathematics to industrial needs are booming across the Asia-Pacific region.</jats:p>

<jats:p>“Self-finance” directive comes as government pushes indigenous innovation.</jats:p>