Catálogo de publicaciones - revistas

<jats:title>Nepal's quake-driven landslide hazards</jats:title> <jats:p> Large earthquakes can trigger dangerous landslides across a wide geographic region. The 2015 <jats:italic>M</jats:italic> <jats:sub>w</jats:sub> 7.8 Gorhka earthquake near Kathmandu, Nepal, was no exception. Kargal <jats:italic>et al.</jats:italic> used remote observations to compile a massive catalog of triggered debris flows. The satellite-based observations came from a rapid response team assisting the disaster relief effort. Schwanghart <jats:italic>et al.</jats:italic> show that Kathmandu escaped the historically catastrophic landslides associated with earthquakes in 1100, 1255, and 1344 C.E. near Nepal's second largest city, Pokhara. These two studies underscore the importance of determining slope stability in mountainous, earthquake-prone regions. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aac8353">10.1126/science.aac8353</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6269" page="147" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aac9865">147</jats:related-article> </jats:p>

<jats:title>Adjusting hematopoietic hierarchy</jats:title> <jats:p> In adults, more than 300 billion blood cells are replenished daily. This output arises from a cellular hierarchy where stem cells differentiate into a series of multilineage progenitors, culminating in unilineage progenitors that generate over 10 different mature blood cell types. Notta <jats:italic>et al.</jats:italic> mapped the lineage potential of nearly 3000 single cells from 33 different cell populations of stem and progenitor cells from fetal liver, cord blood, and adult bone marrow (see the Perspective by Cabezas-Wallscheid and Trumpp). Prenatally, stem cell and progenitor populations were multilineage with few unilineage progenitors. In adults, multilineage cell potential was only seen in stem cell populations. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aab2116">10.1126/science.aab2116</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6269" page="126" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aae0325">126</jats:related-article> </jats:p>

<jats:title>Fine-tuned information flow in the brain</jats:title> <jats:p> In addition to providing well-characterized excitatory inputs, the entorhinal cortex also sends long-range inhibitory projections to the hippocampus. Basu <jats:italic>et al.</jats:italic> described this input in detail and characterized its role for learning and memory. Multimodal sensory stimuli activate long-range inhibitory input in vivo. This input enables precisely timed information transfer within the cortico-hippocampal circuit. In this way, long-range inhibitory projections play an important role in providing specificity of fear conditioning, and thus help prevent overgeneralization. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaa5694">10.1126/science.aaa5694</jats:related-article> </jats:p>

<jats:p>The importance of the agreement reached at the Paris climate Conference of Parties (COP21) last month cannot be overstated. It is a major step toward preventing some of the worst risks that climate change presents to the global economy and security. Now is the time to seize the opportunity that this moment represents. We must transform world economies away from fossil fuels toward a more sustainable low-carbon future.</jats:p>