Catálogo de publicaciones - revistas

<jats:title>Bleaching of the Great Barrier Reef</jats:title> <jats:p> The Australian Great Barrier Reef (GBR) is one of Earth's most extraordinary natural wonders, but it is vulnerable to climate change. Ainsworth <jats:italic>et al.</jats:italic> have tracked the effects of three decades of increasing heat stress on coral organisms. In the past, pulses of elevated temperatures that presaged hot seasons stimulated the acclimation of coral organisms and resilience to thermal stress. More recently, temperature hikes have been severe and precluded acclimation. The result has been increasing bleaching and death; notably extreme during 2016 in the wake of El Niño. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="338" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aac7125">338</jats:related-article> </jats:p>

<jats:title>Carbon trading between adult trees</jats:title> <jats:p> Competition between individual plants for resources is well known, but sharing of resources may also occur. Klein <jats:italic>et al.</jats:italic> observed tree-to-tree carbon shuttling between roots of tall trees in a mixed temperate forest in Switzerland (see the Perspective by van der Heijden). By applying stable carbon isotope labeling to individual tree canopies, they show that up to 40% of the carbon in the fine roots of one individual may be derived from photosynthetic products of a neighbor. Carbon transfer of this kind, mediated by plant-associated fungi, or mycorrhizae, in the soil, has been reported on a smaller scale in seedlings, but not before in trees. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="342" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad6188">342</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="290" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf4694">290</jats:related-article> </jats:p>

<jats:title>Zika virus genomes from Brazil</jats:title> <jats:p> The Zika virus outbreak is a major cause for concern in Brazil, where it has been linked with increased reports of otherwise rare birth defects and neuropathology. In a phylogenetic analysis, Faria <jats:italic>et al.</jats:italic> infer a single introduction of Zika to the Americas and estimated the introduction date to be about May to December 2013—some 12 months earlier than the virus was reported. This timing correlates with major events in the Brazilian cultural calendar associated with increased traveler numbers from areas where Zika virus has been circulating. A correlation was also observed between incidences of microcephaly and week 17 of pregnancy. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="345" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf5036">345</jats:related-article> </jats:p>

<jats:title>Transmission blocked by drug resistance</jats:title> <jats:p> Resistance to the antimalarial drug atovaquone might prove to be this parasite's weak spot. Resistance develops rapidly via mutations in the drug's target: the parasite's mitochondrial cytochrome b complex. Goodman <jats:italic>et al.</jats:italic> have discovered that although resistant <jats:italic>Plasmodium berghei</jats:italic> parasites persist in mice, in blood-sucking malarial mosquitoes, the mutations disable female parasites too much for them to reproduce. The human-specific <jats:italic>Plasmodium falciparum</jats:italic> can only be investigated experimentally in mosquitoes, but a similar effect was seen. Thus, atovaquone-resistant parasites cannot be transmitted to another mammal or person. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="349" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad9279">349</jats:related-article> </jats:p>

<jats:title>Repairing tears in the nuclear envelope</jats:title> <jats:p> The nuclear envelope segregates genomic DNA from the cytoplasm and regulates protein trafficking between the cytosol and the nucleus. Maintaining nuclear envelope integrity during interphase is considered crucial. However, Raab <jats:italic>et al.</jats:italic> and Denais <jats:italic>et al.</jats:italic> show that migrating immune and cancer cells experience frequent and transitory nuclear envelope ruptures when they move through tight spaces (see the Perspective by Burke). The nuclear envelope reseals rapidly during interphase, assisted by components of the ESCRT III membrane-remodeling machinery. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue pp. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="359" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad7611">359</jats:related-article> and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="353" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad7297">353</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="295" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf7735">295</jats:related-article> </jats:p>

<jats:title>Repairing tears in the nuclear envelope</jats:title> <jats:p> The nuclear envelope segregates genomic DNA from the cytoplasm and regulates protein trafficking between the cytosol and the nucleus. Maintaining nuclear envelope integrity during interphase is considered crucial. However, Raab <jats:italic>et al.</jats:italic> and Denais <jats:italic>et al.</jats:italic> show that migrating immune and cancer cells experience frequent and transitory nuclear envelope ruptures when they move through tight spaces (see the Perspective by Burke). The nuclear envelope reseals rapidly during interphase, assisted by components of the ESCRT III membrane-remodeling machinery. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue pp. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="359" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad7611">359</jats:related-article> and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="353" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad7297">353</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="295" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf7735">295</jats:related-article> </jats:p>

<jats:title>Blueprint for a macromolecular machine</jats:title> <jats:p> Nuclear pore complexes (NPCs) consist of around 1000 protein subunits, are embedded in the membrane that surrounds the nucleus, and regulate transport between the nucleus and the cytoplasm. Although the overall shape of NPCs is known, the details of this macromolecular complex have been obscure. Now, Lin <jats:italic>et al.</jats:italic> have reconstituted the pore components, determined the interactions between them, and fitted them into a tomographic reconstruction. Kosinski <jats:italic>et al.</jats:italic> have provided an architectural map of the inner ring of the pore. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue pp. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf1015">10.1126/science.aaf1015</jats:related-article> and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="363" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf0643">363</jats:related-article> </jats:p>

<jats:title>Engineering a healing immune response</jats:title> <jats:p> Infections, surgeries, and trauma can all cause major tissue damage. Biomaterial scaffolds, which help to guide regenerating tissue, are an exciting emerging therapeutic strategy to promote tissue repair. Sadtler <jats:italic>et al.</jats:italic> tested how biomaterial scaffolds interact with the immune system in damaged tissue to promote repair (see the Perspective by Badylak). Scaffolds derived from cardiac muscle and bone extracellular matrix components trigger a tissue-reparative T cell immune response in mice with injured muscles. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="366" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aad9272">366</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6283" page="298" related-article-type="in-this-issue" vol="352" xlink:href="10.1126/science.aaf7587">298</jats:related-article> </jats:p>

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>