Catálogo de publicaciones - revistas

<jats:title>A recipe for intestinal lgA</jats:title> <jats:p> Our guts are teeming with microbes, some friendly and others not. Plasma cells in the gut secrete immunoglobulin A (IgA), which helps to keep the peace with resident commensal bacteria and fights pathogens. B cell isotype switching to IgA occurs in lymphoid tissues called Peyer's patches. Reboldi <jats:italic>et al.</jats:italic> studied the cellular processes that guide B cells toward making IgA in mice. B cells took an unexpected journey from Peyer's patches follicles to the intestinal mucosa to interact with specialized IgA-triggering dendritic cells. The B cells then migrated back to the follicles to become IgA-producing B cells. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf4822">10.1126/science.aaf4822</jats:related-article> </jats:p>

<jats:p> Later this month (23 and 24 May), the United Nations will convene the first World Humanitarian Summit in Istanbul, where global and local leaders will commit to putting each and every person's safety, dignity, freedom, and right to thrive at the heart of decision-making. More than 125 million people are in need of humanitarian assistance, a level of suffering not seen since World War II. The social problems are wide and deep, from war and human trafficking to the gross inequality between the wealthy 1% and the poorest 3 billion of the population. Included in the summit's Agenda for Humanity are climate and natural disasters. Indeed, 1 year ago, Pope Francis emphasized, in the encyclical <jats:italic>Laudato Si</jats:italic> , that complex crises have both social and environmental dimensions. The bond between humans and the natural world means that we live in an “integral ecology,” and as such, an integrated approach to environmental and social justice is required. </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>