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Institución detectada	Período	Navegá	Descargá	Solicitá
No detectada	desde mar. 1997 / hasta dic. 2023	Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

1880-

Cobertura temática

Ciencias naturales

Tabla de contenidos

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doi: 10.1126/science.aag3305

Animal-based antibodies: Obsolete

A. C. Gray; S. S. Sidhu; P. C. Chandrasekera; C. F. M. Hendriksen; C. A. K. Borrebaeck

Palabras clave: Multidisciplinary.

Pp. 452-453

doi: 10.1126/science.aaf1288

Comment on “Multiple repressive mechanisms in the hippocampus during memory formation”

Rebecca S. Mathew; Hillary Mullan; Jan Krzysztof Blusztajn; Maria K. Lehtinen

<jats:p> Cho <jats:italic>et al</jats:italic> . (Reports, 2 October 2015, p. 82) report that gene repression after contextual fear conditioning regulates hippocampal memory formation. We observe low levels of expression for many of the top candidate genes in the hippocampus and robust expression in the choroid plexus, as well as repression at 4 hours after contextual fear conditioning, suggesting the inclusion of choroid plexus messenger RNAs in Cho <jats:italic>et al</jats:italic> . hippocampal samples. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 453-453

doi: 10.1126/science.aah3551

The line between science and politics

Mel Weintraub

Palabras clave: Multidisciplinary.

Pp. 453-453

doi: 10.1126/science.aaf2081

Response to Comment on “Multiple repressive mechanisms in the hippocampus during memory formation”

Jun Cho; Nam-Kyung Yu; V. Narry Kim; Bong-Kiun Kaang

<jats:p> Mathew <jats:italic>et al</jats:italic> . propose that many candidate genes identified in our study may reflect the events in the choroid plexus (ChP) potentially included in hippocampal samples. We reanalyze our data and find that the ChP inclusion is unlikely to affect our major conclusions regarding the basal suppression of translational machinery or the early translational repression (at 5 to 10 minutes). As Mathew <jats:italic>et al</jats:italic> . examined for a subset of genes at 4 hours, we agree that the late suppression may partly reflect the events in the ChP. Although the precise contribution of anatomical sources remains to be clarified, our behavioral analyses indicate that the late-phase suppression of these genes may contribute to memory formation. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 453-453

doi: 10.1126/science.353.6298.455