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Science
Resumen/Descripción – provisto por la editorial
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Palabras clave – provistas por la editorial
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation
Yuki Taya; Yasunori Ota; Adam C. Wilkinson; Ayano Kanazawa; Hiroshi Watarai; Masataka Kasai; Hiromitsu Nakauchi; Satoshi Yamazaki
<jats:p>Hematopoietic stem cell maintenance requires the amino acid valine.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1152-1155
Self-renewal of a purified Tie2 + hematopoietic stem cell population relies on mitochondrial clearance
Kyoko Ito; Raphaël Turcotte; Jinhua Cui; Samuel E. Zimmerman; Sandra Pinho; Toshihide Mizoguchi; Fumio Arai; Judith M. Runnels; Clemens Alt; Julie Teruya-Feldstein; Jessica C. Mar; Rajat Singh; Toshio Suda; Charles P. Lin; Paul S. Frenette; Keisuke Ito
<jats:p>Purified hematopoietic stem cells reveal that mitophagy plays a key role in their expansion.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1156-1160
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Kristen E. Pauken; Morgan A. Sammons; Pamela M. Odorizzi; Sasikanth Manne; Jernej Godec; Omar Khan; Adam M. Drake; Zeyu Chen; Debattama R. Sen; Makoto Kurachi; R. Anthony Barnitz; Caroline Bartman; Bertram Bengsch; Alexander C. Huang; Jason M. Schenkel; Golnaz Vahedi; W. Nicholas Haining; Shelley L. Berger; E. John Wherry
<jats:p>Epigenetic profiling suggests that exhausted T cells are a distinct cell linage.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1160-1165
The epigenetic landscape of T cell exhaustion
Debattama R. Sen; James Kaminski; R. Anthony Barnitz; Makoto Kurachi; Ulrike Gerdemann; Kathleen B. Yates; Hsiao-Wei Tsao; Jernej Godec; Martin W. LaFleur; Flavian D. Brown; Pierre Tonnerre; Raymond T. Chung; Damien C. Tully; Todd M. Allen; Nicole Frahm; Georg M. Lauer; E. John Wherry; Nir Yosef; W. Nicholas Haining
<jats:p>Epigenetic profiling suggests that exhausted T cells are a distinct cell linage.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1165-1169
Generation of influenza A viruses as live but replication-incompetent virus vaccines
Longlong Si; Huan Xu; Xueying Zhou; Ziwei Zhang; Zhenyu Tian; Yan Wang; Yiming Wu; Bo Zhang; Zhenlan Niu; Chuanling Zhang; Ge Fu; Sulong Xiao; Qing Xia; Lihe Zhang; Demin Zhou
<jats:p>Genetic code expansion and orthogonal translation machinery are used to generate live, attenuated viral vaccines.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1170-1173
New Products
<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 1174-1174
Webinar | Characterizing the maternal immune environment during pregnancy: Implications for autism spectrum disorders
Karen Jones; Anthony Saporita
<jats:p> Under normal conditions, the maternal immune system is uniquely regulated during pregnancy to maintain a pathogen-free, yet noninflammatory environment for the developing fetus. However, factors such as cytokines and chemokines produced during gestation can have developmental consequences for the fetus. In particular, maternal immune dysregulation during pregnancy has been frequently associated with increased risk of autism spectrum disorders. This webinar will discuss the relationship between the maternal immune environment and autism risk, highlighting findings from the largest population-based prospective study to date to have examined the relationship between mid-gestational maternal cytokines and chemokines and risk for autism. <jats:list list-type="bullet"> <jats:list-item> <jats:p> <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://webinar.sciencemag.org/webinar/archive/characterizing-maternal-immune-environment-during-pregnancy-implications-autism">View the Webinar</jats:ext-link> </jats:p> </jats:list-item> </jats:list> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 1174-1174
Making a difference, differently
Matthew Tuthill
Palabras clave: Multidisciplinary.
Pp. 1194-1194
Healthier blueberries, thanks to a blast of purple plasma
Ula Chrobak
Palabras clave: Multidisciplinary.
Pp. No disponible
Museum curator resigns after investigations of sexual misconduct
Ann Gibbons
Palabras clave: Multidisciplinary.
Pp. No disponible