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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Breathing control center neurons that promote arousal in mice

Kevin YackleORCID; Lindsay A. SchwarzORCID; Kaiwen KamORCID; Jordan M. Sorokin; John R. HuguenardORCID; Jack L. FeldmanORCID; Liqun LuoORCID; Mark A. KrasnowORCID

<jats:p>A tiny group of neurons in the brainstem matches breathing rate to the level of calmness versus arousal.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1411-1415

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites

M. DawidowskiORCID; L. EmmanouilidisORCID; V. C. KalelORCID; K. TripsianesORCID; K. SchorppORCID; K. HadianORCID; M. KaiserORCID; P. MäserORCID; M. Kolonko; S. TangheORCID; A. Rodriguez; W. Schliebs; R. ErdmannORCID; M. SattlerORCID; G. M. PopowiczORCID

<jats:p>A drug that inhibits trafficking of proteins into a peroxisome-like organelle in trypanosomes causes lethal metabolic catastrophe.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1416-1420

The whole-soil carbon flux in response to warming

Caitlin E. Hicks PriesORCID; C. CastanhaORCID; R. C. Porras; M. S. TornORCID

<jats:p> Warming the top meter increased soil CO­ <jats:sub>2</jats:sub> production by 37%, with 40% of the response coming from soils more than 15 centimeters deep. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1420-1423

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

Alice O. KamphorstORCID; Andreas WielandORCID; Tahseen NastiORCID; Shu YangORCID; Ruan Zhang; Daniel L. Barber; Bogumila T. Konieczny; Candace Z. Daugherty; Lydia Koenig; Ke Yu; Gabriel L. Sica; Arlene H. SharpeORCID; Gordon J. FreemanORCID; Bruce R. BlazarORCID; Laurence A. Turka; Taofeek K. Owonikoko; Rathi N. Pillai; Suresh S. Ramalingam; Koichi Araki; Rafi AhmedORCID

<jats:p>Immunotherapeutic PD-1–targeted therapies require CD28 to promote cancer cell killing.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1423-1427

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

Enfu HuiORCID; Jeanne CheungORCID; Jing Zhu; Xiaolei SuORCID; Marcus J. Taylor; Heidi A. WallweberORCID; Dibyendu K. Sasmal; Jun Huang; Jeong M. Kim; Ira MellmanORCID; Ronald D. ValeORCID

<jats:p>Immunotherapeutic PD-1–targeted therapies require CD28 to promote cancer cell killing.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1428-1433

Aging increases cell-to-cell transcriptional variability upon immune stimulation

Celia Pilar Martinez-JimenezORCID; Nils ElingORCID; Hung-Chang ChenORCID; Catalina A. VallejosORCID; Aleksandra A. KolodziejczykORCID; Frances ConnorORCID; Lovorka StojicORCID; Timothy F. RaynerORCID; Michael J. T. StubbingtonORCID; Sarah A. TeichmannORCID; Maike de la Roche; John C. MarioniORCID; Duncan T. OdomORCID

<jats:p>Single-cell sequencing of mouse immune cells reveals how aging destabilizes a conserved transcriptional activation program.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1433-1436

On the origins of oxygenic photosynthesis and aerobic respiration in Cyanobacteria

Rochelle M. SooORCID; James HempORCID; Donovan H. Parks; Woodward W. FischerORCID; Philip HugenholtzORCID

<jats:p>Oxygen-producing photosynthesis and oxygen-consuming respiration evolved after the divergence of the main lineages of blue-green algae.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1436-1440

New Products

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1441-1441

Creating our own community

Cecilia Sánchez; Anya Brown

Palabras clave: Multidisciplinary.

Pp. 1446-1446

Norway plans to exterminate a large reindeer herd to stop a fatal infectious brain disease

Erik Stokstad

Palabras clave: Multidisciplinary.

Pp. No disponible