Catálogo de publicaciones - revistas

<jats:title>Having your longevity and eating too</jats:title> <jats:p> Although caloric restriction has clear benefits for maximizing health span and life span, it is sufficiently unpleasant that few humans stick to it. Madeo <jats:italic>et al.</jats:italic> review evidence that increased intake of the polyamine spermidine appears to reproduce many of the healthful effects of caloric restriction, and they explain its cellular actions, which include enhancement of autophagy and protein deacetylation. Spermidine is found in foods such as wheat germ, soybeans, nuts, and some fruits and vegetables and produced by the microbiota. Increased uptake of spermidine has protective effects against cancer, metabolic disease, heart disease, and neurodegeneration. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aan2788">eaan2788</jats:related-article> </jats:p>

<jats:p>The comment by Myers-Smith and Myers focuses on three main points: (i) the lack of a mechanistic explanation for climate-selection relationships, (ii) the appropriateness of the climate data used in our analysis, and (iii) our focus on estimating climate-selection relationships across (rather than within) taxonomic groups. We address these critiques in our response.</jats:p>

<jats:p> Siepielski <jats:italic>et al</jats:italic> . (Reports, 3 March 2017, p. 959) claim that “precipitation drives global variation in natural selection.” This conclusion is based on a meta-analysis of the relationship between climate variables and natural selection measured in wild populations of invertebrates, plants, and vertebrates. Three aspects of this analysis cause concern: (i) lack of within-year climate variables, (ii) low and variable estimates of covariance relationships across taxa, and (iii) a lack of mechanistic explanations for the patterns observed; association is not causation. </jats:p>

<jats:p>It is the best of times. It is the worst of times. We are witnessing major advances in almost every field of science, leading to a better understanding of the world and improvements in the quality of people's lives. Yet, scattered distrust of science, neglect of science by public officials, and frequent denial of scientific thinking in many quarters seem to call into question that rosy view of scientific progress. The inconsistency indicates widespread misunderstanding of what science is and how it works. It is up to scientists to fix this.</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Scientists say their labmade virus could make a new smallpox vaccine. Others call it a “mistake” and a “stunt.”</jats:p>

<jats:p>Falcon Heavy could enable faster, heavier, cheaper missions.</jats:p>

<jats:p>Amid probe of many brain disorders, ENIGMA finds common structural changes in diverse kinds of epilepsy.</jats:p>

<jats:p>Verdict expected soon in trial of dual-nationality scientist accused of terrorism.</jats:p>

<jats:p>Scientists probe ways that storms weaponize pollen.</jats:p>