Catálogo de publicaciones - revistas

<jats:title>Mapping the vertebrate developmental landscape</jats:title> <jats:p> As embryos develop, numerous cell types with distinct functions and morphologies arise from pluripotent cells. Three research groups have used single-cell RNA sequencing to analyze the transcriptional changes accompanying development of vertebrate embryos (see the Perspective by Harland). Wagner <jats:italic>et al.</jats:italic> sequenced the transcriptomes of more than 90,000 cells throughout zebrafish development to reveal how cells differentiate during axis patterning, germ layer formation, and early organogenesis. Farrell <jats:italic>et al.</jats:italic> profiled the transcriptomes of tens of thousands of embryonic cells and applied a computational approach to construct a branching tree describing the transcriptional trajectories that lead to 25 distinct zebrafish cell types. The branching tree revealed how cells change their gene expression as they become more and more specialized. Briggs <jats:italic>et al.</jats:italic> examined whole frog embryos, spanning zygotic genome activation through early organogenesis, to map cell states and differentiation across all cell lineages over time. These data and approaches pave the way for the comprehensive reconstruction of transcriptional trajectories during development. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="981" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aar4362">981</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aar3131">eaar3131</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aar5780">eaar5780</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="967" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat8413">967</jats:related-article> </jats:p>

<jats:title>The global impacts of food production</jats:title><jats:p>Food is produced and processed by millions of farmers and intermediaries globally, with substantial associated environmental costs. Given the heterogeneity of producers, what is the best way to reduce food's environmental impacts? Poore and Nemecek consolidated data on the multiple environmental impacts of ∼38,000 farms producing 40 different agricultural goods around the world in a meta-analysis comparing various types of food production systems. The environmental cost of producing the same goods can be highly variable. However, this heterogeneity creates opportunities to target the small numbers of producers that have the most impact.</jats:p><jats:p><jats:italic>Science</jats:italic>, this issue p.<jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="987" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aaq0216">987</jats:related-article></jats:p>

<jats:title>Methane ice dunes on Pluto</jats:title> <jats:p> Wind-blown sand or ice dunes are known on Earth, Mars, Venus, Titan, and comet 67P/Churyumov-Gerasimenko. Telfer <jats:italic>et al.</jats:italic> used images taken by the New Horizons spacecraft to identify dunes in the Sputnik Planitia region on Pluto (see the Perspective by Hayes). Modeling shows that these dunes could be formed by sand-sized grains of solid methane ice transported in typical Pluto winds. The methane grains could have been lofted into the atmosphere by the melting of surrounding nitrogen ice or blown down from nearby mountains. Understanding how dunes form under Pluto conditions will help with interpreting similar features found elsewhere in the solar system. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="992" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aao2975">992</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="960" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat7488">960</jats:related-article> </jats:p>

<jats:title>I've got a feeling</jats:title> <jats:p> Sensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials of organic electronics, Kim <jats:italic>et al.</jats:italic> combined a pressure sensor, a ring oscillator, and an ion gel–gated transistor to form an artificial mechanoreceptor (see the Perspective by Bartolozzi). The combination allows for the sensing of multiple pressure inputs, which can be converted into a sensor signal and used to drive the motion of a cockroach leg in an oscillatory pattern. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="998" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aao0098">998</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="966" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat3125">966</jats:related-article> </jats:p>

<jats:title>Triggering quakes in a geothermal space</jats:title> <jats:p> Enhanced geothermal systems (EGSs) provide a potentially clean and abundant energy source. However, two magnitude-5 earthquakes recently occurred in South Korea during EGS site development. Grigoli <jats:italic>et al.</jats:italic> and Kim <jats:italic>et al.</jats:italic> present seismic and geophysical evidence that may implicate the second of these earthquakes, which occurred in Pohang, as an induced event. The combination of data from a local seismometer network, well logs, satellite observations, teleseismic waveform analysis, and stress modeling leads to the assessment that the earthquake was probably or almost certainly anthropogenically induced. The possibility remains that the earthquake occurred coincidentally at the EGS site location, but the aftershock distribution and other lines of evidence are concerning for future development of this geothermal resource. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="1003" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat2010">1003</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="1007" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat6081">1007</jats:related-article> </jats:p>

<jats:title>Triggering quakes in a geothermal space</jats:title> <jats:p> Enhanced geothermal systems (EGSs) provide a potentially clean and abundant energy source. However, two magnitude-5 earthquakes recently occurred in South Korea during EGS site development. Grigoli <jats:italic>et al.</jats:italic> and Kim <jats:italic>et al.</jats:italic> present seismic and geophysical evidence that may implicate the second of these earthquakes, which occurred in Pohang, as an induced event. The combination of data from a local seismometer network, well logs, satellite observations, teleseismic waveform analysis, and stress modeling leads to the assessment that the earthquake was probably or almost certainly anthropogenically induced. The possibility remains that the earthquake occurred coincidentally at the EGS site location, but the aftershock distribution and other lines of evidence are concerning for future development of this geothermal resource. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="1003" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat2010">1003</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6392" page="1007" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aat6081">1007</jats:related-article> </jats:p>