Catálogo de publicaciones - revistas

<jats:title>Chronic stress as a survival tactic</jats:title> <jats:p> Most patients with pancreatic ductal adenocarcinoma (PDA) develop liver metastases after surgical removal of their primary tumor. These metastases are thought to potentially arise from quiescent disseminated cancer cells, likely present at the time of surgery, which evade elimination by the immune system. Pommier <jats:italic>et al.</jats:italic> explored how these quiescent cells survive by analyzing mouse models and tissue samples from patients with PDA. They found that disseminated cancer cells do not express a cell surface molecule that triggers killing by T cells. This phenotypic feature is linked to their inability to resolve endoplasmic reticulum stress. When this stress is resolved, the disseminated cells begin proliferating and form metastases. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aao4908">eaao4908</jats:related-article> </jats:p>

<jats:p>Today, the global HIV epidemic is widely viewed as triumph over tragedy. This stands in stark contrast to the first two decades of the epidemic, when AIDS was synonymous with suffering and death. But have we turned the tide on HIV sufficiently to warrant directing our attention and investments elsewhere?</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p> Scientists scramble to explain unusual bloom of <jats:italic>Sargassum</jats:italic> weed. </jats:p>

<jats:p>Pending legislation seeks to counter foreign investment in quantum computing and related technologies.</jats:p>

<jats:p>National Academies study urges cultural change to curb multiple kinds of sexual harassment.</jats:p>

<jats:p>Method offers a low-cost way to fill seismic detection gaps.</jats:p>

<jats:p>Entry permission cut to 1 year for graduate students in some STEM fields.</jats:p>

<jats:p>The world has rallied around the goal of "ending AIDS" but Russia, Nigeria, and Florida stand out for their faltering responses to HIV.</jats:p>

<jats:p>Nigeria struggles to slow the spread of HIV to babies.</jats:p>