Catálogo de publicaciones - revistas

<jats:title>Cross-talk in the mammary gland</jats:title> <jats:p> Macrophages engulf damaged and dead cells to clear infection, but they also participate in tissue regeneration. Chakrabarti <jats:italic>et al.</jats:italic> expand the macrophage repertoire for mammary gland development (see the Perspective by Kannan and Eaves). Mammary gland stem cells secrete the Notch ligand Dll1 and activate Notch signaling, which promotes survival of adjacent macrophages. This stimulates production of Wnt ligands, which signal back to the mammary gland stem cells. This cross-talk plays an important role in coordinating mammary gland development, tissue homeostasis, and, not least, breast cancer. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aan4153">eaan4153</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6396" page="1401" related-article-type="in-this-issue" vol="360" xlink:href="10.1126/science.aau1394">1401</jats:related-article> </jats:p>

<jats:title>Path to zero carbon emissions</jats:title> <jats:p> Models show that to avert dangerous levels of climate change, global carbon dioxide emissions must fall to zero later this century. Most of these emissions arise from energy use. Davis <jats:italic>et al.</jats:italic> review what it would take to achieve decarbonization of the energy system. Some parts of the energy system are particularly difficult to decarbonize, including aviation, long-distance transport, steel and cement production, and provision of a reliable electricity supply. Current technologies and pathways show promise, but integration of now-discrete energy sectors and industrial processes is vital to achieve minimal emissions. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aas9793">eaas9793</jats:related-article> </jats:p>

<jats:title>Imaging dopamine release in the brain</jats:title> <jats:p> Neuromodulator release alters the function of target circuits in poorly known ways. An essential step to address this knowledge gap is to measure the dynamics of neuromodulatory signals while simultaneously manipulating the elements of the target circuit during behavior. Patriarchi <jats:italic>et al.</jats:italic> developed fluorescent protein–based dopamine indicators to visualize spatial and temporal release of dopamine directly with high fidelity and resolution. In the cortex, two-photon imaging with these indicators was used to map dopamine activity at cellular resolution. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aat4422">eaat4422</jats:related-article> </jats:p>

<jats:p> Our planet is in a perilous state. The combined effects of climate change, pollution, and loss of biodiversity are putting our health and well-being at risk. Given that human actions are largely responsible for these global problems, humanity must now nudge Earth onto a trajectory toward a more stable, harmonious state. Many of the challenges are daunting, but solutions can be found. In this issue of <jats:italic>Science</jats:italic> , we launch a series of monthly articles that call attention to some of the choices we can still make for shaping tomorrow's Earth—commentaries and analyses that will hopefully provoke us to making thoughtful choices (see <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://scim.ag/TomorrowsEarth">scim.ag/TomorrowsEarth</jats:ext-link> ). </jats:p>

<jats:p>A roundup of weekly science policy and related news</jats:p>

<jats:p>Free, web-based beacons could be used in commerce, politics, and science</jats:p>

<jats:p>Young researchers champion good conduct and push for offenders to be punished</jats:p>

<jats:p>Decision on spinal muscular atrophy due next week</jats:p>

<jats:p>Solar windows absorb ultraviolet and infrared light while letting visible light pass through</jats:p>

<jats:p>Counting tumor mutations could identify right treatment</jats:p>