Catálogo de publicaciones - revistas

<jats:title>Magnons propagating in graphene</jats:title> <jats:p> At sufficiently low temperatures, a two-dimensional electron system placed in an external magnetic field can exhibit the so-called quantum Hall effect. In this regime, a variety of magnetic phases may occur, depending on the electron density and other factors. Wei <jats:italic>et al.</jats:italic> studied the properties of these exotic magnetic phases in graphene. They generated magnons—the excitations of an ordered magnetic system—that were then absorbed by the sample, leaving a mark on its electrical conductance. The magnons were able to propagate across long distances through various magnetic phases in the bulk graphene. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="229" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aar4061">229</jats:related-article> </jats:p>

<jats:title>Keeping the doors open for symbiosis</jats:title> <jats:p> Nitrogen fixation by legumes results from a symbiotic partnership between plant and microbes. These together elaborate nodules on the plant roots that house the bacteria. Tsikou <jats:italic>et al.</jats:italic> identified a microRNA made in the aboveground shoots of <jats:italic>Lotus japonicus</jats:italic> that translocates to the plant's roots. In the roots, the microRNA posttranscriptionally regulates a key suppressor of symbiosis, thus keeping the uninfected root susceptible to productive infection by symbiotic bacteria. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="233" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aat6907">233</jats:related-article> </jats:p>

<jats:title>Cas12 inhibitors join the anti-CRISPR family</jats:title> <jats:p> Bacteria and their phages continually coevolve in a molecular arms race. For example, phages use anti-CRISPR proteins to inhibit the bacterial type I and II CRISPR systems (see the Perspective by Koonin and Makarova). Watters <jats:italic>et al.</jats:italic> and Marino <jats:italic>et al.</jats:italic> used bioinformatic and experimental approaches to identify inhibitors of type V CRISPR-Cas12a. Cas12a has been successfully engineered for gene editing and nucleic acid detection. Some of the anti-Cas12a proteins identified in these studies had broad-spectrum inhibitory effects on Cas12a orthologs and could block Cas12a-mediated genome editing in human cells. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="236" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aau5138">236</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="240" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aau5174">240</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="156" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aav2440">156</jats:related-article> </jats:p>

<jats:title>Cas12 inhibitors join the anti-CRISPR family</jats:title> <jats:p> Bacteria and their phages continually coevolve in a molecular arms race. For example, phages use anti-CRISPR proteins to inhibit the bacterial type I and II CRISPR systems (see the Perspective by Koonin and Makarova). Watters <jats:italic>et al.</jats:italic> and Marino <jats:italic>et al.</jats:italic> used bioinformatic and experimental approaches to identify inhibitors of type V CRISPR-Cas12a. Cas12a has been successfully engineered for gene editing and nucleic acid detection. Some of the anti-Cas12a proteins identified in these studies had broad-spectrum inhibitory effects on Cas12a orthologs and could block Cas12a-mediated genome editing in human cells. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="236" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aau5138">236</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="240" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aau5174">240</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6411" page="156" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aav2440">156</jats:related-article> </jats:p>

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

<jats:p>Advances in biosensors and microfluidic devices are driving a quiet revolution in biomedical research, which could lead to the reduction or elimination of animal use in many experiments..</jats:p>