Catálogo de publicaciones - revistas

<jats:title>The future of farming</jats:title> <jats:p>In the mid-20th century, food production from agriculture sharply increased worldwide; however, this was achieved through heavy use of agrochemicals. Extensive collateral damage from excessive use of pesticides, herbicides, and fertilizers has occurred to the wider environment. This has led to biodiversity loss, pesticide resistance and the emergence of new pests, pollution and decline of freshwater supplies, and soil degradation and erosion, as well as direct harm to health. In a Review, Pretty examines the alternative approaches that can achieve sustainable intensification of farming systems by integrating pest management with agroecological systems to minimize costs, maximize yields, restore ecosystem services, and ensure environmental enhancement.</jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aav0294">eaav0294</jats:related-article> </jats:p>

<jats:title>Myofibroblast diversity with injury and aging</jats:title> <jats:p> Fibroblasts deposit extracellular matrix (ECM) molecules to regulate tissue strength and function. However, if too much ECM is deposited, fibrosis and scarring results. Shook <jats:italic>et al.</jats:italic> examined cells during mouse skin wound healing, fibrosis, and aging (see the Perspective by Willenborg and Eming). They identified distinct subpopulations of myofibroblasts, including cells identified as adipocyte precursors (APs). In cellular ablation mouse models, CD301b-expressing macrophages selectively activated proliferation of APs, but not other myofibroblasts. Myofibroblast composition and gene expression changed during aging. Thus, macrophage-fibroblast interactions are important during tissue repair and aging, which may have therapeutic implications for chronic wounds and fibrotic disease. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aar2971">eaar2971</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6417" page="891" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aav5542">891</jats:related-article> </jats:p>

<jats:title>Maternal factor sets axis</jats:title> <jats:p> The vertebrate body form changes from the round shape of the fertilized egg to a cylindrical shape when the body plan is established. However, it is unknown whether a maternal factor controls this body axis formation. Yan <jats:italic>et al.</jats:italic> identified such a maternal factor and named it Huluwa. Loss of maternal Huluwa, a transmembrane protein, in zebrafish or frog eggs resulted in embryos that lacked the body axis and were missing the head and dorsoanterior tissues. Huluwa promoted Axin degradation, likely independent of Wnt ligand–receptor signaling, to protect β-catenin from degradation and induce body axis development during embryogenesis. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aat1045">eaat1045</jats:related-article> </jats:p>

<jats:p>Data breaches at Facebook and Google—and along with Amazon, those firms' online dominance—crest a growing wave of anxiety around the internet's evolving structure and its impact on humanity. Three keys to the decades-long global expansion of the internet and the World Wide Web are breaking down.</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>REV Ocean ramps up with $500 million from Norwegian fisheries and oil tycoon.</jats:p>

<jats:p>Experiments on commercial landers could confirm a wetter, more active moon.</jats:p>

<jats:p>Cell mimics make and pass on proteins that influence their neighbors.</jats:p>

<jats:p>China unveils full design for a $5 billion collider; Japan nears decision on its own plan.</jats:p>