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<jats:p>The Second International Summit on Human Genome Editing, held in Hong Kong last month, was rocked by the revelation from a researcher from Shenzhen that twins were born whose healthy embryonic genomes had been edited to confer resistance to HIV. Despite widespread condemnation by the summit organizing committee, world scientific academies, and prominent scientific leaders that such research was “deeply disturbing” and “irresponsible,” and the launch of an investigation in China into the researcher's actions, it is apparent that the ability to use CRISPR-Cas9 to edit the human genome has outpaced nascent efforts by the scientific and medical communities to confront the complex ethical and governance issues that they raise. The current guidelines and principles on human germline genome editing are based on sound scientific and ethical principles. However, this case highlights the urgent need to accelerate efforts to reach international agreement upon more specific criteria and standards that have to be met before human germline editing would be deemed permissible.</jats:p>

<jats:p> Climate change is a tragedy of the commons of existential importance. At the annual United Nations climate summit that concludes this week, parties will affirm the necessity to avoid dangerous climate change. But between now and next year's summit, these same countries will in many ways act so as to hasten the outcome that they say must be avoided. This disjunction between what countries say and what they do has been repeated every year since the first summit in 1995. It is a pattern of behavior that seems irrational, but that can be explained. American ecologist Garrett Hardin's classic article, “The Tragedy of the Commons,” published in <jats:italic>Science</jats:italic> 50 years ago this week, vividly describes the dilemma that causes this behavior (see page 1236). </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Harvested from drained and denuded bogs, peat is more polluting than coal.</jats:p>

<jats:p>NIH ordered staff scientists not to procure new tissue.</jats:p>

<jats:p>Independent panel calls for replacing executive director.</jats:p>

<jats:p>DRC conflict hampers effort to track and contain virus.</jats:p>

<jats:p>GEDI data will yield maps of forest carbon and biodiversity.</jats:p>

<jats:p>Regulatory DNA takes center stage in search for mechanisms of disease.</jats:p>

<jats:p>Wire-free devices that dissolve could expand the use of electric pulses in medicine.</jats:p>