Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Knocking down neurodegeneration
Michael Funk (eds.)
Palabras clave: Multidisciplinary.
Pp. 1438.9-1440
Editors' Choice
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439-1440
A mitotic error code
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.1-1439
In search of a male contraceptive
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.2-1440
A silver lining for hurricanes
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.3-1440
Feed the dog
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.4-1440
Determining odd from even
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.5-1440
It's in the air
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.6-1440
A strange strange metal
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 1439.7-1440
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Renhong Yan
; Yuanyuan Zhang; Yaning Li; Lu Xia; Yingying Guo; Qiang Zhou
<jats:title>How SARS-CoV-2 binds to human cells</jats:title> <jats:p> Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral trimeric spike protein to the human receptor angiotensin-converting enzyme 2 (ACE2). Yan <jats:italic>et al.</jats:italic> present the structure of human ACE2 in complex with a membrane protein that it chaperones, B <jats:sup>0</jats:sup> AT1. In the context of this complex, ACE2 is a dimer. A further structure shows how the receptor binding domain of SARS-CoV-2 interacts with ACE2 and suggests that it is possible that two trimeric spike proteins bind to an ACE2 dimer. The structures provide a basis for the development of therapeutics targeting this crucial interaction. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6485" page="1444" related-article-type="in-this-issue" vol="367" xlink:href="10.1126/science.abb2762">1444</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 1444-1448