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Science

Resumen/Descripción – provisto por la editorial

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Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

After claims of sex bias, scientific leader at NIH’s child health institute withdraws from new job

Meredith Wadman

Palabras clave: Multidisciplinary.

Pp. No disponible

‘We will have many body bags.’ WHO chief responds to Trump’s criticisms

Jon Cohen

Palabras clave: Multidisciplinary.

Pp. No disponible

Elaborately decorated eggs predate Easter by thousands of years

Michael Price

Palabras clave: Multidisciplinary.

Pp. No disponible

For survivors of severe COVID-19, beating the virus is just the beginning

Kelly Servick

Palabras clave: Multidisciplinary.

Pp. No disponible

Watch out Silicon Valley: European Union gets into the venture capital game

Nicholas Wallace

Palabras clave: Multidisciplinary.

Pp. No disponible

How a gene from a grass-living fungus could save wheat crops worldwide

Erik Stokstad

Palabras clave: Multidisciplinary.

Pp. No disponible

How I’ve connected with other scientists online during the COVID-19 pandemic

Arpit Sharma

Palabras clave: Multidisciplinary.

Pp. No disponible

Is France’s president fueling the hype over an unproven coronavirus treatment?

Yves Sciama

Palabras clave: Multidisciplinary.

Pp. No disponible

Metabolic reprogramming and cancer progression

Brandon FaubertORCID; Ashley SolmonsonORCID; Ralph J. DeBerardinisORCID

<jats:title>Metabolism as cancer progresses</jats:title> <jats:p> Numerous cancer-specific alterations in metabolism have been identified but have not yet resulted in an effective anti cancer therapeutic. In a Review, Faubert <jats:italic>et al.</jats:italic> discuss how metabolism changes as cancer develops from a small, premalignant lesion to an aggressive primary tumor and then metastasizes. Metabolic vulnerabilities likely change with cancer progression, making the identification of general cancer-associated metabolic features difficult. The authors propose that a more targeted approach to tissues and vulnerabilities identified in patients may be more effective. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaw5473">eaaw5473</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Transcription polymerase–catalyzed emergence of novel RNA replicons

Nimit JainORCID; Lucas R. BlauchORCID; Michal R. SzymanskiORCID; Rhiju DasORCID; Sindy K. Y. TangORCID; Y. Whitney YinORCID; Andrew Z. FireORCID

<jats:title>Revisiting replicating RNAs</jats:title> <jats:p> DNA-dependent RNA polymerases are well known for their ability to produce RNA from DNA templates. Much less is known about their noncanonical activity: the generation and replication of RNA from RNA templates. Deeper insights into this process could shed light on questions relating to the origin of life, molecular evolution, and the replication of certain RNA pathogens such as hepatitis delta virus and plant viroids. Jain <jats:italic>et al.</jats:italic> explore in detail how the bacteriophage T7 RNA polymerase generates and amplifies diverse RNA sequences in vitro. Using sequencing, microfluidics, and bioinformatics, they chart the emergence and evolution of replicating RNA motifs and identify mechanisms that explain their selection and structures. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aay0688">eaay0688</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible