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Science
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Ratcheting quasi-ballistic electrons in silicon geometric diodes at room temperature
James P. Custer
; Jeremy D. Low
; David J. Hill
; Taylor S. Teitsworth
; Joseph D. Christesen
; Collin J. McKinney
; James R. McBride
; Martin A. Brooke
; Scott C. Warren
; James F. Cahoon
<jats:title>Room-temperature electron ratchets</jats:title> <jats:p> Conventional diodes rectify current flow by forming a junction between dissimilar conductors; a metal-semiconductor diode that forms a Schottky barrier is one example. In these devices, capacitance limits operating frequency. Custer <jats:italic>et al.</jats:italic> describe a diode made entirely of silicon that can rectify currents up to 40 gigahertz at room temperature. They fabricated silicon nanowires with a cylindrical sawtooth profile that act as ratchets, funneling current preferentially in one direction through specular reflection of quasi-ballistic electrons. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="177" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aay8663">177</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 177-180
Intravital imaging of mouse embryos
Qiang Huang
; Malkiel A. Cohen
; Fernando C. Alsina
; Garth Devlin; Aliesha Garrett
; Jennifer McKey
; Patrick Havlik; Nikolai Rakhilin; Ergang Wang
; Kun Xiang
; Parker Mathews; Lihua Wang; Cheryl Bock; Victor Ruthig
; Yi Wang
; Marcos Negrete
; Chi Wut Wong
; Preetish K. L. Murthy
; Shupei Zhang; Andrea R. Daniel
; David G. Kirsch
; Yubin Kang
; Blanche Capel
; Aravind Asokan
; Debra L. Silver
; Rudolf Jaenisch
; Xiling Shen
<jats:title>A window to the embryo</jats:title> <jats:p> Mammalian embryonic development is a complex process, continuously changing in space and time. Q. Huang <jats:italic>et al.</jats:italic> designed an abdominal window to image mouse embryos in utero from embryonic day 9.5 to birth. Using this technique, they visualized dynamic activities during embryonic organ formation, including neurotransmission and cell division in the brain, autophagy in the retina, viral gene delivery, and placental drug transfer. They also tracked diverging fates of human and mouse neural crest cells in interspecies chimeras. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="181" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aba0210">181</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 181-186
Dendritic cell–derived hepcidin sequesters iron from the microbiota to promote mucosal healing
Nicholas J. Bessman
; Jacques R. R. Mathieu; Cyril Renassia; Lei Zhou; Thomas C. Fung
; Keith C. Fernandez
; Christine Austin
; Jesper B. Moeller
; Sara Zumerle
; Sabine Louis; Sophie Vaulont; Nadim J. Ajami
; Harry Sokol
; Gregory G. Putzel; Tara Arvedson
; Robbyn E. Sockolow
; Samira Lakhal-Littleton
; Suzanne M. Cloonan
; Manish Arora; Carole Peyssonnaux
; Gregory F. Sonnenberg
<jats:title>Ironing out the details of mucosal healing</jats:title> <jats:p> Anemia is a frequent complication of disorders such as inflammatory bowel disease, occurring in part as a result of increased bleeding into the intestine. Bessman <jats:italic>et al.</jats:italic> show that the peptide hormone hepcidin, which regulates systemic iron homeostasis, is required for intestinal repair in a mouse model of inflammatory bowel disease (see the Perspective by Rescigno). This effect was independent of hepatocyte-produced hepcidin and systemic iron levels. Instead, production of hepcidin by conventional dendritic cells was necessary and sufficient to promote local iron sequestration by macrophages, which in turn modulated the makeup of the gut microbiota to one with a more beneficial distribution of species. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="186" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aau6481">186</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="129" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abb2915">129</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 186-189
Bose polarons near quantum criticality
Zoe Z. Yan
; Yiqi Ni
; Carsten Robens
; Martin W. Zwierlein
<jats:title>Immersing the impurities</jats:title> <jats:p> In solids, moving electrons can polarize their environment, the ionic crystal lattice, creating quasi particles known as polarons. An analogous phenomenon can be studied in quantum gases by placing impurity atoms into a much denser gas of atoms of a different species. Yan <jats:italic>et al.</jats:italic> studied the behavior of Bose polarons, quasiparticles consisting of impurity atoms of potassium-40 immersed in a Bose gas of sodium-23 atoms. In the vicinity of a quantum critical point, the lifetime of the polarons followed the so-called Planckian scale. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="190" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aax5850">190</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 190-194
A parapithecid stem anthropoid of African origin in the Paleogene of South America
Erik R. Seiffert
; Marcelo F. Tejedor; John G. Fleagle
; Nelson M. Novo
; Fanny M. Cornejo
; Mariano Bond
; Dorien de Vries; Kenneth E. Campbell
<jats:title>A South American anthropoid</jats:title> <jats:p> Although there are many primate lineages in the Old World, it is thought that the New World is home to just one group, the platyrrhine monkeys, which appear to have colonized the region during the Eocene. Seiffert <jats:italic>et al.</jats:italic> describe a new primate species on the basis of fossil molars found in the Peruvian Amazon that appears to belong to the Parapithecidae, a group of stem anthropoid primates best known from northern Africa (see the Perspective by Godinot). The fossils appear to be from a well-differentiated lineage, suggesting that this species had been evolving within South America for some time. It is likely that the ancestors of this new species arrived via a transatlantic rafting event when sea levels dropped at the Eocene–Oligocene transition ∼32 to 35 million years ago. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="194" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aba1135">194</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="136" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abb4107">136</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 194-197
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
Ashley E. Lepack
; Craig T. Werner
; Andrew F. Stewart
; Sasha L. Fulton; Ping Zhong
; Lorna A. Farrelly; Alexander C. W. Smith
; Aarthi Ramakrishnan
; Yang Lyu
; Ryan M. Bastle
; Jennifer A. Martin
; Swarup Mitra; Richard M. O’Connor; Zi-Jun Wang; Henrik Molina
; Gustavo Turecki; Li Shen
; Zhen Yan
; Erin S. Calipari
; David M. Dietz
; Paul J. Kenny; Ian Maze
<jats:title>More than a normal neurotransmitter</jats:title> <jats:p> The molecular mechanisms underlying the persistence of addiction remain largely unclear. Lepack <jats:italic>et al.</jats:italic> found that, with cocaine exposure, there is an intracellular accumulation of dopamine in neurons of a brain region called the ventral tegmental area (see the Perspective by Girault). Dopamine associates with chromatin to initiate a previously unknown form of epigenetic regulation called dopaminylation. This modification has an impact on ventral tegmental area function and, consequently, on dopaminergic action potentials. The result is aberrant dopamine signaling in the ventral striatum during periods of drug seeking. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="197" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aaw8806">197</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6487" page="134" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abb3533">134</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 197-201
New Products
<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 202-202
Finding community during a pandemic
Arpit Sharma
Palabras clave: Multidisciplinary.
Pp. 206-206
Mice, hamsters, ferrets, monkeys. Which lab animals can help defeat the new coronavirus?
Jon Cohen
Palabras clave: Multidisciplinary.
Pp. No disponible
How the first visitor to our Solar System may have formed—no alien technology required
Sid Perkins
Palabras clave: Multidisciplinary.
Pp. No disponible