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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Coronavirus dons a new crown

Nuruddin Unchwaniwala; Paul Ahlquist

Palabras clave: Multidisciplinary.

Pp. 1306-1307

Flossie Wong-Staal (1946–2020)

Genoveffa Franchini

Palabras clave: Multidisciplinary.

Pp. 1308-1308

An ethical framework for global vaccine allocation

Ezekiel J. Emanuel; Govind Persad; Adam Kern; Allen Buchanan; Cécile Fabre; Daniel Halliday; Joseph Heath; Lisa Herzog; R. J. Leland; Ephrem T. Lemango; Florencia Luna; Matthew S. McCoy; Ole F. Norheim; Trygve Ottersen; G. Owen Schaefer; Kok-Chor Tan; Christopher Heath Wellman; Jonathan Wolff; Henry S. Richardson

Palabras clave: Multidisciplinary.

Pp. 1309-1312

NIH must confront the use of race in science

Jennifer Sills (eds.)

Palabras clave: Multidisciplinary.

Pp. 1313-1314

Accumulation of plastic waste during COVID-19

Jennifer Sills (eds.)

Palabras clave: Multidisciplinary.

Pp. 1314-1315

Microplastic's role in antibiotic resistance

Jennifer Sills (eds.)

Palabras clave: Multidisciplinary.

Pp. 1315-1315

The custom transcriptome

Laura M. Zahn

Palabras clave: Multidisciplinary.

Pp. 1316-1317

The GTEx Consortium atlas of genetic regulatory effects across human tissues

<jats:p>The Genotype-Tissue Expression (GTEx) project was established to characterize genetic effects on the transcriptome across human tissues and to link these regulatory mechanisms to trait and disease associations. Here, we present analyses of the version 8 data, examining 15,201 RNA-sequencing samples from 49 tissues of 838 postmortem donors. We comprehensively characterize genetic associations for gene expression and splicing in cis and trans, showing that regulatory associations are found for almost all genes, and describe the underlying molecular mechanisms and their contribution to allelic heterogeneity and pleiotropy of complex traits. Leveraging the large diversity of tissues, we provide insights into the tissue specificity of genetic effects and show that cell type composition is a key factor in understanding gene regulatory mechanisms in human tissues.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1318-1330

Gravitational lenses in galaxy clusters

Michael Funk (eds.)

Palabras clave: Multidisciplinary.

Pp. 1335.1-1335

The role of sex in the human transcriptome

Michael Funk (eds.)

Palabras clave: Multidisciplinary.

Pp. 1335.10-1337