Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Editors' Choice
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71-72
Leprosy-associated genetics
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.1-71
A sintering-avoiding support
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.2-72
Recovery from paralysis
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.3-72
Corrosion detection and protection in one
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.4-72
Characterizing the menstrual cycle
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.5-72
Exercise circuit for training
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.6-72
Three elements to increase diversity
Caroline Ash; Jesse Smith (eds.)
Palabras clave: Multidisciplinary.
Pp. 71.7-72
Extensive heterogeneity in somatic mutation and selection in the human bladder
Andrew R. J. Lawson
; Federico Abascal; Tim H. H. Coorens; Yvette Hooks; Laura O’Neill; Calli Latimer; Keiran Raine; Mathijs A. Sanders; Anne Y. Warren; Krishnaa T. A. Mahbubani; Bethany Bareham; Timothy M. Butler; Luke M. R. Harvey; Alex Cagan; Andrew Menzies; Luiza Moore; Alexandra J. Colquhoun; William Turner; Benjamin Thomas; Vincent Gnanapragasam; Nicholas Williams; Doris M. Rassl; Harald Vöhringer; Sonia Zumalave; Jyoti Nangalia; José M. C. Tubío; Moritz Gerstung; Kourosh Saeb-Parsy; Michael R. Stratton; Peter J. Campbell; Thomas J. Mitchell; Iñigo Martincorena
<jats:title>Genetic profiles of the bladder</jats:title> <jats:p> Depending on the environment of the individual, the human bladder can be exposed to carcinogens as they are flushed through the body. Lawson <jats:italic>et al.</jats:italic> and Li <jats:italic>et al.</jats:italic> examined the genetic composition of laser-dissected microbiopsies from normal and cancer cells collected from the urothelium, a specialized epithelium lining the lower urinary tract (see the Perspective by Rozen). These complementary studies identified the mutational landscape of bladder urothelium through various sequencing strategies and identified high mutational heterogeneity within and between individuals and tumors. Both studies identified mutational profiles related to specific carcinogens such as aristolochic acid and the molecules found in tobacco. These studies present a comprehensive description of the diverse mutational landscape of the human bladder in health and disease, unraveling positive selection for cancer-causing mutations, a diversity of mutational processes, and large differences across individuals. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="75" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.aba8347">75</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="82" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.aba7300">82</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="34" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.abe0955">34</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 75-82
Macroscopic somatic clonal expansion in morphologically normal human urothelium
Ruoyan Li; Yiqing Du; Zhanghua Chen; Deshu Xu; Tianxin Lin; Shanzhao Jin; Gongwei Wang; Ziyang Liu; Min Lu; Xu Chen; Tao Xu; Fan Bai
<jats:title>Genetic profiles of the bladder</jats:title> <jats:p> Depending on the environment of the individual, the human bladder can be exposed to carcinogens as they are flushed through the body. Lawson <jats:italic>et al.</jats:italic> and Li <jats:italic>et al.</jats:italic> examined the genetic composition of laser-dissected microbiopsies from normal and cancer cells collected from the urothelium, a specialized epithelium lining the lower urinary tract (see the Perspective by Rozen). These complementary studies identified the mutational landscape of bladder urothelium through various sequencing strategies and identified high mutational heterogeneity within and between individuals and tumors. Both studies identified mutational profiles related to specific carcinogens such as aristolochic acid and the molecules found in tobacco. These studies present a comprehensive description of the diverse mutational landscape of the human bladder in health and disease, unraveling positive selection for cancer-causing mutations, a diversity of mutational processes, and large differences across individuals. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="75" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.aba8347">75</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="82" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.aba7300">82</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6512" page="34" related-article-type="in-this-issue" vol="370" xlink:href="10.1126/science.abe0955">34</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 82-89