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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

A physical map of the human Y chromosome

Charles A. Tilford; Tomoko Kuroda-Kawaguchi; Helen Skaletsky; Steve Rozen; Laura G. Brown; Michael Rosenberg; John D. McPherson; Kristine Wylie; Mandeep Sekhon; Tamara A. Kucaba; Robert H. Waterston; David C. Page

Palabras clave: Multidisciplinary.

Pp. 943-945

A high-resolution map of human chromosome 12

Kate T. Montgomery; Eunice Lee; Ashley Miller; Stephanie Lau; Cecilia Shim; Jeremy Decker; Denise Chiu; Suzanne Emerling; Mandeep Sekhon; Rachel Kim; Jack Lenz; Jinghua Han; Ilya Ioshikhes; Beatrice Renault; Ivonne Marondel; Sung-Joo Kim Yoon; Kyuyoung Song; V. V. V. S. Murty; Steven Scherer; Raluca Yonescu; Ilan R. Kirsch; Thomas Ried; John McPherson; Richard Gibbs; Raju Kucherlapati

Palabras clave: Multidisciplinary.

Pp. 945-946

A physical map of human chromosome 14

Thomas Brüls; Gabor Gyapay; Jean-Louis Petit; François Artiguenave; Virginie Vico; Shizen Qin; Aye Mon Tin-Wollam; Corinne Da Silva; Delphine Muselet; Delphine Mavel; Eric Pelletier; Michael Levy; Asao Fujiyama; Fumihiko Matsuda; Richard Wilson; Lee Rowen; Leroy Hood; Jean Weissenbach; William Saurin; Roland Heilig

Palabras clave: Multidisciplinary.

Pp. 947-948

Integration of telomere sequences with the draft human genome sequence

H. C. Riethman; Z. Xiang; S. Paul; E. Morse; X.-L. Hu; J. Flint; H.-C. Chi; D. L. Grady; R. K. Moyzis

Palabras clave: Multidisciplinary.

Pp. 948-951

Comparison of human genetic and sequence-based physical maps

Adong Yu; Chengfeng Zhao; Ying Fan; Wonhee Jang; Andrew J. Mungall; Panos Deloukas; Anne Olsen; Norman A. Doggett; Nader Ghebranious; Karl W. Broman; James L. Weber

Palabras clave: Multidisciplinary.

Pp. 951-953

Integration of cytogenetic landmarks into the draft sequence of the human genome

The BAC Resource Consortium; V. G. Cheung; N. Nowak; W. Jang; I. R. Kirsch; S. Zhao; X.-N. Chen; T. S. Furey; U.-J. Kim; W.-L. Kuo; M. Olivier; J. Conroy; A. Kasprzyk; H. Massa; R. Yonescu; S. Sait; C. Thoreen; A. Snijders; E. Lemyre; J. A. Bailey; A. Bruzel; W. D. Burrill; S. M. Clegg; S. Collins; P. Dhami; C. Friedman; C. S. Han; S. Herrick; J. Lee; A. H. Ligon; S. Lowry; M. Morley; S. Narasimhan; K. Osoegawa; Z. Peng; I. Plajzer-Frick; B. J. Quade; D. Scott; K. Sirotkin; A. A. Thorpe; J. W. Gray; J. Hudson; D. Pinkel; T. Ried; L. Rowen; G. L. Shen-Ong; R. L. Strausberg; E. Birney; D. F. Callen; J.-F. Cheng; D. R. Cox; N. A. Doggett; N. P. Carter; E. E. Eichler; D. Haussler; J. R. Korenberg; C. C. Morton; D. Albertson; G. Schuler; P. J. de Jong; B. J. Trask

<jats:title>Abstract</jats:title><jats:p>We have placed 7,600 cytogenetically defined landmarks on the draft sequence of the human genome to help with the characterization of genes altered by gross chromosomal aberrations that cause human disease. The landmarks are large-insert clones mapped to chromosome bands by fluorescence <jats:italic>in situ</jats:italic> hybridization. Each clone contains a sequence tag that is positioned on the genomic sequence. This genome-wide set of sequence-anchored clones allows structural and functional analyses of the genome. This resource represents the first comprehensive integration of cytogenetic, radiation hybrid, linkage and sequence maps of the human genome; provides an independent validation of the sequence map<jats:sup>1,2</jats:sup> and framework for contig order and orientation; surveys the genome for large-scale duplications, which are likely to require special attention during sequence assembly; and allows a stringent assessment of sequence differences between the dark and light bands of chromosomes. It also provides insight into large-scale chromatin structure and the evolution of chromosomes and gene families and will accelerate our understanding of the molecular bases of human disease and cancer.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 953-958

Microarrays, DNA and RNA prep

Palabras clave: Multidisciplinary.

Pp. 959-960

Following the growth of data

Potter Wickware

Palabras clave: Multidisciplinary.

Pp. 961-961

Labs and companies seek their niches as work continues after the draft

Potter Wickware; Paul Smaglik

Palabras clave: Multidisciplinary.

Pp. 961-963

Who makes the best bioinformaticians?

Paul Smaglik

Palabras clave: Multidisciplinary.

Pp. 963-963