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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
| No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
Coupling of activity, metabolism and behaviour across the Drosophila brain
Kevin Mann; Stephane Deny; Surya Ganguli; Thomas R. Clandinin
Palabras clave: Multidisciplinary.
Pp. 244-248
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy
Sandro Da Mesquita; ; Zachary Papadopoulos; Taitea Dykstra; Logan Brase; Fabiana Geraldo Farias; Morgan Wall; Hong Jiang; Chinnappa Dilip Kodira; Kalil Alves de Lima; Jasmin Herz; Antoine Louveau; Dylan H. Goldman; Andrea Francesca Salvador; Suna Onengut-Gumuscu; Emily Farber; Nisha Dabhi; Tatiana Kennedy; Mary Grace Milam; Wendy Baker; Igor Smirnov; Stephen S. Rich; Bruno A. Benitez; Celeste M. Karch; Richard J. Perrin; Martin Farlow; Jasmeer P. Chhatwal; David M. Holtzman; Carlos Cruchaga; Oscar Harari; Jonathan Kipnis
Palabras clave: Multidisciplinary.
Pp. 255-260
C. difficile exploits a host metabolite produced during toxin-mediated disease
Kali M. Pruss; Justin L. Sonnenburg
Palabras clave: Multidisciplinary.
Pp. 261-265
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England
Erik Volz; ; Swapnil Mishra; Meera Chand; Jeffrey C. Barrett; Robert Johnson; Lily Geidelberg; Wes R. Hinsley; Daniel J. Laydon; Gavin Dabrera; Áine O’Toole; Robert Amato; Manon Ragonnet-Cronin; Ian Harrison; Ben Jackson; Cristina V. Ariani; Olivia Boyd; Nicholas J. Loman; John T. McCrone; Sónia Gonçalves; David Jorgensen; Richard Myers; Verity Hill; David K. Jackson; Katy Gaythorpe; Natalie Groves; John Sillitoe; Dominic P. Kwiatkowski; Seth Flaxman; Oliver Ratmann; Samir Bhatt; Susan Hopkins; Axel Gandy; Andrew Rambaut; Neil M. Ferguson
Palabras clave: Multidisciplinary.
Pp. 266-269
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7
Nicholas G. Davies; ; Christopher I. Jarvis; W. John Edmunds; Nicholas P. Jewell; Karla Diaz-Ordaz; Ruth H. Keogh
Palabras clave: Multidisciplinary.
Pp. 270-274
A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease
Shikha Nayar; Joshua K. Morrison; Mamta Giri; Kyle Gettler; Ling-shiang Chuang; Laura A. Walker; Huaibin M. Ko; Ephraim Kenigsberg; Subra Kugathasan; Miriam Merad; Jaime Chu; Judy H. Cho
Palabras clave: Multidisciplinary.
Pp. 275-281
Cell-programmed nutrient partitioning in the tumour microenvironment
Bradley I. Reinfeld; Matthew Z. Madden; Melissa M. Wolf; Anna Chytil; Jackie E. Bader; Andrew R. Patterson; Ayaka Sugiura; Allison S. Cohen; Ahmed Ali; Brian T. Do; Alexander Muir; Caroline A. Lewis; Rachel A. Hongo; Kirsten L. Young; Rachel E. Brown; Vera M. Todd; Tessa Huffstater; Abin Abraham; Richard T. O’Neil; Matthew H. Wilson; Fuxue Xin; M. Noor Tantawy; W. David Merryman; Rachelle W. Johnson; Christopher S. Williams; Emily F. Mason; Frank M. Mason; Katherine E. Beckermann; Matthew G. Vander Heiden; H. Charles Manning; Jeffrey C. Rathmell; W. Kimryn Rathmell
Palabras clave: Multidisciplinary.
Pp. 282-288
HP1 drives de novo 3D genome reorganization in early Drosophila embryos
Fides Zenk; Yinxiu Zhan; Pavel Kos; Eva Löser; Nazerke Atinbayeva; Melanie Schächtle; Guido Tiana; Luca Giorgetti; Nicola Iovino
<jats:title>Abstract</jats:title><jats:p>Fundamental features of 3D genome organization are established de novo in the early embryo, including clustering of pericentromeric regions, the folding of chromosome arms and the segregation of chromosomes into active (A-) and inactive (B-) compartments. However, the molecular mechanisms that drive de novo organization remain unknown<jats:sup>1,2</jats:sup>. Here, by combining chromosome conformation capture (Hi-C), chromatin immunoprecipitation with high-throughput sequencing (ChIP–seq), 3D DNA fluorescence in situ hybridization (3D DNA FISH) and polymer simulations, we show that heterochromatin protein 1a (HP1a) is essential for de novo 3D genome organization during <jats:italic>Drosophila</jats:italic> early development. The binding of HP1a at pericentromeric heterochromatin is required to establish clustering of pericentromeric regions. Moreover, HP1a binding within chromosome arms is responsible for overall chromosome folding and has an important role in the formation of B-compartment regions. However, depletion of HP1a does not affect the A-compartment, which suggests that a different molecular mechanism segregates active chromosome regions. Our work identifies HP1a as an epigenetic regulator that is involved in establishing the global structure of the genome in the early embryo.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 289-293
Structural basis of long-range to short-range synaptic transition in NHEJ
Siyu Chen; Linda Lee; Tasmin Naila; Susan Fishbain; Annie Wang; Alan E. Tomkinson; Susan P. Lees-Miller; Yuan He
Palabras clave: Multidisciplinary.
Pp. 294-298
How to blow the whistle on an academic bully
Virginia Gewin
Palabras clave: Multidisciplinary.
Pp. 299-301