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Resumen/Descripción – provisto por la editorial

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Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

In killing citizenship question, Trump adopts Census Bureau’s preferred solution to a thorny problem

Jeffrey Mervis

Palabras clave: Multidisciplinary.

Pp. No disponible

Is the Western mind too WEIRD to study?

Kai Kupferschmidt

Palabras clave: Multidisciplinary.

Pp. No disponible

In a first, a Japanese spacecraft appears to have collected samples from inside an asteroid

Dennis Normile

Palabras clave: Multidisciplinary.

Pp. No disponible

Amid concerns about grad student mental health, one university takes a novel approach

Katie Langin

Palabras clave: Multidisciplinary.

Pp. No disponible

Anthrax-carrying flies follow monkeys through the forest

Eva Frederick

Palabras clave: Multidisciplinary.

Pp. No disponible

Late Pleistocene exploration and settlement of the Americas by modern humans

Michael R. WatersORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Response to Comment on “Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality”

Michael J. MinaORCID; Bryan T. Grenfell; C. Jessica E. MetcalfORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Comment on “Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality”

Niket ThakkarORCID; Kevin A. McCarthyORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

Jeanette L. GehrigORCID; Siddarth Venkatesh; Hao-Wei ChangORCID; Matthew C. HibberdORCID; Vanderlene L. KungORCID; Jiye ChengORCID; Robert Y. ChenORCID; Sathish Subramanian; Carrie A. CowardinORCID; Martin F. Meier; David O’DonnellORCID; Michael TalcottORCID; Larry D. SpearsORCID; Clay F. SemenkovichORCID; Bernard HenrissatORCID; Richard J. GiannoneORCID; Robert L. HettichORCID; Olga Ilkayeva; Michael MuehlbauerORCID; Christopher B. Newgard; Christopher SawyerORCID; Richard D. Head; Dmitry A. RodionovORCID; Aleksandr A. ArzamasovORCID; Semen A. LeynORCID; Andrei L. OstermanORCID; Md Iqbal Hossain; Munirul Islam; Nuzhat Choudhury; Shafiqul Alam Sarker; Sayeeda Huq; Imteaz Mahmud; Ishita Mostafa; Mustafa MahfuzORCID; Michael J. BarrattORCID; Tahmeed Ahmed; Jeffrey I. GordonORCID

<jats:p>To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state of Bangladeshi children with severe acute malnutrition (SAM) as they transitioned, after standard treatment, to moderate acute malnutrition (MAM) with persistent microbiota immaturity. Host and microbial effects of microbiota-directed complementary food (MDCF) prototypes targeting weaning-phase bacterial taxa underrepresented in SAM and MAM microbiota were characterized in gnotobiotic mice and gnotobiotic piglets colonized with age- and growth-discriminatory bacteria. A randomized, double-blind controlled feeding study identified a lead MDCF that changes the abundances of targeted bacteria and increases plasma biomarkers and mediators of growth, bone formation, neurodevelopment, and immune function in children with MAM.</jats:p>

Palabras clave: Multidisciplinary.

Pp. eaau4732

A sparse covarying unit that describes healthy and impaired human gut microbiota development

Arjun S. RamanORCID; Jeanette L. GehrigORCID; Siddarth Venkatesh; Hao-Wei ChangORCID; Matthew C. HibberdORCID; Sathish Subramanian; Gagandeep Kang; Pascal O. Bessong; Aldo A.M. Lima; Margaret N. Kosek; William A. PetriORCID; Dmitry A. RodionovORCID; Aleksandr A. ArzamasovORCID; Semen A. LeynORCID; Andrei L. OstermanORCID; Sayeeda Huq; Ishita Mostafa; Munirul Islam; Mustafa MahfuzORCID; Rashidul Haque; Tahmeed Ahmed; Michael J. BarrattORCID; Jeffrey I. GordonORCID

<jats:p>Characterizing the organization of the human gut microbiota is a formidable challenge given the number of possible interactions between its components. Using a statistical approach initially applied to financial markets, we measured temporally conserved covariance among bacterial taxa in the microbiota of healthy members of a Bangladeshi birth cohort sampled from 1 to 60 months of age. The results revealed an “ecogroup” of 15 covarying bacterial taxa that provide a concise description of microbiota development in healthy children from this and other low-income countries, and a means for monitoring community repair in undernourished children treated with therapeutic foods. Features of ecogroup population dynamics were recapitulated in gnotobiotic piglets as they transitioned from exclusive milk feeding to a fully weaned state consuming a representative Bangladeshi diet.</jats:p>

Palabras clave: Multidisciplinary.

Pp. eaau4735