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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Climate-Forced Variability of Ocean Hypoxia

Curtis Deutsch; Holger Brix; Taka Ito; Hartmut Frenzel; LuAnne Thompson

<jats:p>The spatial extent of ocean hypoxic zones, which are uninhabitable by many marine organisms, is very sensitive to dioxygen content.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 336-339

Chirality in Planar Cell Shape Contributes to Left-Right Asymmetric Epithelial Morphogenesis

Kiichiro Taniguchi; Reo Maeda; Tadashi Ando; Takashi Okumura; Naotaka Nakazawa; Ryo Hatori; Mitsutoshi Nakamura; Shunya Hozumi; Hiroo Fujiwara; Kenji Matsuno

<jats:p>Left-right asymmetry in cell shape is converted to a directional twist of the gut epithelial tube.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 339-341

Control of Mitotic Spindle Angle by the RAS-Regulated ERK1/2 Pathway Determines Lung Tube Shape

Nan Tang; Wallace F. Marshall; Martin McMahon; Ross J. Metzger; Gail R. Martin

<jats:p>During lung development, airway shape is determined by a signaling pathway that regulates the orientation of cell division.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 342-345

Electrical Spiking in Escherichia coli Probed with a Fluorescent Voltage-Indicating Protein

Joel M. Kralj; Daniel R. Hochbaum; Adam D. Douglass; Adam E. Cohen

<jats:title>Introducing Bacterial Electrophysiology</jats:title> <jats:p> Bacterial electrophysiology has been limited by the inability to measure the membrane potential of single cells. <jats:bold> Kralj <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="345" related-article-type="in-this-issue" vol="333" xlink:href="10.1126/science.1204763">345</jats:related-article> ) engineered a class of voltage-sensitive fluorescent membrane proteins to perform electrophysiological measurements on individual intact bacteria. These measurements showed that <jats:italic>Escherichia coli</jats:italic> generate electrical spikes, reminiscent of action potentials in neurons. The response of electrical spiking in bacteria was assessed in response to a wide range of physical and chemical perturbations, and was correlated with efflux activity. In the future, the probe should be useful in determining the roles of membrane potential in a variety of medically, environmentally, and industrially important bacteria. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 345-348

Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement

Farren J. Isaacs; Peter A. Carr; Harris H. Wang; Marc J. Lajoie; Bram Sterling; Laurens Kraal; Andrew C. Tolonen; Tara A. Gianoulis; Daniel B. Goodman; Nikos B. Reppas; Christopher J. Emig; Duhee Bang; Samuel J. Hwang; Michael C. Jewett; Joseph M. Jacobson; George M. Church

<jats:p>Template-mediated, genome construction and assembly created a strain with 80 precise codon changes.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 348-353

Linking Context with Reward: A Functional Circuit from Hippocampal CA3 to Ventral Tegmental Area

Alice H. Luo; Pouya Tahsili-Fahadan; Roy A. Wise; Carl R. Lupica; Gary Aston-Jones

<jats:p>A hippocampus–to–ventral tegmental area pathway regulates dopamine neurons and is necessary for reinstatement of context-induced cocaine-seeking.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 353-357

Life at the Top: Rank and Stress in Wild Male Baboons

Laurence R. Gesquiere; Niki H. Learn; M. Carolina M. Simao; Patrick O. Onyango; Susan C. Alberts; Jeanne Altmann

<jats:p>Alpha males have higher stress levels than beta males in a wild baboon society.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 357-360

School-Based Early Childhood Education and Age-28 Well-Being: Effects by Timing, Dosage, and Subgroups

Arthur J. Reynolds; Judy A. Temple; Suh-Ruu Ou; Irma A. Arteaga; Barry A. B. White

<jats:p>A little bit of preschool goes a long way.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 360-364

Science Podcast

<jats:p>The show includes the effects of Google on memory, the stressful lives of alpha male baboons, science in Egypt, and more.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 365-365

New Products

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 365-365