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<jats:p>Computer scientists breathed a sigh of relief last week when the University of Illinois announced that Cray Inc. has agreed to take over the construction of a stalled $200 million supercomputer.</jats:p>

<jats:p>How the United Nations Educational, Scientific and Cultural Organization responds to the sudden loss of U.S. dollars will determine the fate of its roughly $120-million-a-year science portfolio.</jats:p>

<jats:p>We live in the golden age of genetics, but the fundamental unit of biology is still arguably the cell. The scientists gathering next week in Denver for the American Society for Cell Biology's annual meeting need little reminding of that, but as they detail their latest insights and data, it's useful to reflect on how much of the cell remains unexplained or unknown.</jats:p>

<jats:p>Many scientists argue that the molecular platforms that sail on the cell's outer membrane, known as lipid rafts, either don't exist or have no biological relevance, but their supporters insist the idea remains afloat.</jats:p>

<jats:p>Researchers have finally begun to identify potential size-sensing mechanisms within cells, but they admit there's still a lot to learn.</jats:p>

<jats:p>Somehow, a cell must get all its proteins to their correct destinations—and keep these molecules out of the wrong places. The mystery of how cells place their protein repertoire is far from solved.</jats:p>

<jats:p>Cell biologists might be close to learning where the internal membrane comes from that a hungry cell sprouts to encapsulate some of its contents and break them down for reuse.</jats:p>

<jats:p>How the pattern of chromosomes and subnuclear bodies in the cell nucleus affects gene activity and other cellular functions is an enduring mystery in biology, one that won't be unraveled soon.</jats:p>

<jats:p>There are many mysteries that are likely to keep cell biologists working long hours, including how do cells know where they are, how do they sense chemical gradients, and how do they migrate together.</jats:p>

<jats:p>With dangerous global warming seemingly inevitable, users of climate information—from water utilities to international aid workers—are turning to climate scientists for guidance. But usable knowledge is in short supply.</jats:p>