Catálogo de publicaciones - revistas

<jats:p>A key concept in economics and engineering is used to deduce which traits and which tasks that an organism performs are important for fitness.</jats:p>

<jats:p>Ongoing radionuclide monitoring and tracking efforts are required following the nuclear accident at the Fukushima Daiichi Nuclear Power Plant.</jats:p>

<jats:p>Knowledge of the processes that drive tsunami sediment erosion and deposition can help to determine and mitigate tsunami risk.</jats:p>

<jats:p>A magnitude 8.6 strike-slip earthquake within an oceanic plate raises fundamental questions about earthquake physics.</jats:p>

<jats:p>Negative regulation of B cell receptor signaling may contribute to B cell selection and cell fate determination in germinal centers.</jats:p>

<jats:p>The Kepler space telescope can determine the mass and orbital period of unseen planets orbiting distant stars.</jats:p>

<jats:p>An efficient quantum algorithm for solving quantum field theory equations can be applied even to difficult cases that include strong particle interactions.</jats:p>

<jats:title>Designer Hydrogels</jats:title> <jats:p> Hydrogels, which consist of highly water swollen cross-linked polymer networks, can now be made with a range of chemistries and a combination of physical and chemical cross-links. They can also be designed to degrade gradually when exposed to chemical or biological signals and are thus finding use in a wide range of applications, including tissue engineering and drug delivery. <jats:bold>Seliktar</jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1124" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1214804">1124</jats:related-article> ) reviews recent advances in tailoring hydrogels with specific properties and their applications to biology and medicine. </jats:p>

<jats:title>Design and Build</jats:title> <jats:p> Self-assembling biomolecules are attractive building blocks in the development of functional materials. Sophisticated DNA-based materials have been developed; however, progress in designing protein-based materials has been slower. <jats:bold> King <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1171" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1219364">1171</jats:related-article> ) describe a general computational method in which protein building blocks are first symmetrically docked onto a target architecture, and then binding interfaces that drive self-assembly of the building blocks are designed. As a proof of principle, trimeric building blocks were used to design self-assembling 12-subunit complexes with tetrahedral symmetry and 24-subunit complexes with octahedral symmetry. <jats:bold> Lai <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1129" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1219351">1129</jats:related-article> ) were able to build a 12-subunit tetrahedral protein cage from fused oligomeric protein domains. </jats:p>

<jats:title>Quantum Leap?</jats:title> <jats:p> Quantum computers are expected to be able to solve some of the most difficult problems in mathematics and physics. It is not known, however, whether quantum field theories (QFTs) can be simulated efficiently with a quantum computer. QFTs are used in particle and condensed matter physics and have an infinite number of degrees of freedom; discretization is necessary to simulate them digitally. <jats:bold> Jordan <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1130" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1217069">1130</jats:related-article> ; see the Perspective by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6085" page="1122" related-article-type="in-this-issue" vol="336" xlink:href="10.1126/science.1223010"> <jats:bold> Hauke <jats:italic>et al.</jats:italic> </jats:bold> </jats:related-article> ) present an algorithm for the efficient simulation of a particular kind of QFT (with quartic interactions) and estimate the error caused by discretization. Even for the most difficult case of strong interactions, the run time of the algorithm was polynomial (rather than exponential) in parameters such as the number of particles, their energy, and the prescribed precision, making it much more efficient than the best classical algorithms. </jats:p>