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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Little Emperors Pose Behavioral Challenges

Lisa Cameron; Nisvan Erkal; Lata Gangadharan; Xin Meng

Palabras clave: Multidisciplinary.

Pp. 272-273

Comment on “ Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters”

Tobias Straub; Peter B. Becker

<jats:p> Conrad <jats:italic>et al</jats:italic> . (Reports, 10 August 2012, p. 742) reported that <jats:italic>Drosophila</jats:italic> dosage compensation might largely be due to increased recruitment of RNA polymerase II to promoters. A reassessment of the numerical operations revealed that the authors’ calculations are severely confounded by an inappropriate numerical procedure. A rectified analysis strongly suggests that the authors’ conclusions are not supported by their data. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 273-273

Corrections and Clarifications

Palabras clave: Multidisciplinary.

Pp. 273-273

Comment on “ Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters”

F. Ferrari; Y. L. Jung; P. V. Kharchenko; A. Plachetka; A. A. Alekseyenko; M. I. Kuroda; P. J. Park

<jats:p> Conrad <jats:italic>et al</jats:italic> . (Reports, 10 August 2012, p. 742) reported a doubling of RNA polymerase II (Pol II) occupancy at X-linked promoters to support 5′ recruitment as the key mechanism for dosage compensation in <jats:italic>Drosophila</jats:italic> . However, they employed an erroneous data-processing step, overestimating Pol II differences. Reanalysis of the data fails to support the authors’ model for dosage compensation. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 273-273

Response to Comments on “ Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters”

Juan M. Vaquerizas; Florence M. G. Cavalli; Thomas Conrad; Asifa Akhtar; Nicholas M. Luscombe

<jats:p> Ferrari <jats:italic>et al</jats:italic> . and Straub and Becker wrongly claim that an error in the computational analysis calls into question the conclusions of Conrad <jats:italic>et al</jats:italic> . All the available evidence, including the reanalyzed genomic data, show that the conclusions and the key message of the study remain unchanged: RNA polymerase II recruitment to male X-linked promoters is an important regulatory step during dosage compensation. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 273-273

Preventing Prejudice in Genome Profiling

Mahiben Maruthappu; Alexander E. Finlayson

Palabras clave: Multidisciplinary.

Pp. 273-273

Did You Feel It? The Earthquake Observers Disaster Science from Lisbon to Richter by Deborah R. Coen University of Chicago Press, Chicago, 2013. 356 pp. $35,

Gregory C. Beroza

<jats:p>In this history of seismology and its impact, Coen focuses on the contributions of human observers—citizens as well as scientists.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 274-275

Serpentine Figures in Edinburgh Edinburgh International Science Festival Various venues, Edinburgh, Scotland. Through 7 April 2013. www.sciencefestival.co.uk/

Deborah Dixon; Elizabeth Straughan

<jats:p>Our reviewers sample some of the art-science events at this year's Edinburgh International Science Festival.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 275-275

Books Received

<jats:p> A <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.sciencemag.org/site/feature/data/books/brl6130.xhtml">listing of books received</jats:ext-link> at <jats:italic>Science</jats:italic> during the week ending 12 April 2013. </jats:p>

Palabras clave: Multidisciplinary.

Pp. 275-275

Opportunities and Challenges in Next Generation Standards

E. K. Stage; H. Asturias; T. Cheuk; P. A. Daro; S. B. Hampton

<jats:p>Goals for literacy, math, and science education may increase citizens' capacity to argue from evidence.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 276-277