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<jats:p> Iron- or cobalt-based catalysts have outperformed traditional precious metal catalysts in several hydrogenation reactions. <jats:named-content content-type="related-content"> [Also see Reports by <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1073" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1242005"> Jagadeesh <jats:italic>et al.</jats:italic> </jats:related-article> , <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1076" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1243550"> Friedfeld <jats:italic>et al.</jats:italic> </jats:related-article> , and <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1080" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1244466"> Zuo <jats:italic>et al.</jats:italic> </jats:related-article> ] </jats:named-content> </jats:p>

<jats:p>Devices designed for low-resource settings can improve access to life-saving health care around the world.</jats:p>

<jats:p>Metagenomic approaches are rapidly expanding our knowledge of microbial metabolic potential.</jats:p>

<jats:p>A geneticist championed baker's yeast as a model system and inspired and trained many scientists in the field.</jats:p>

<jats:p>The Evolution of Human Mate Preference, an IBI prize–winning module, uses inquiry to elucidate strategies used by males and females to maximize reproductive fitness.</jats:p>

<jats:p> A monthly roundup of recent news and projects of <jats:italic>Science</jats:italic> 's publisher, the American Association for the Advancement of Science. </jats:p>

<jats:title>Deep Impact?</jats:title> <jats:p> On 15 February 2013, the Russian district of Chelyabinsk, with a population of more than 1 million, suffered the impact and atmospheric explosion of a 20-meter-wide asteroid—the largest impact on Earth by an asteroid since 1908. <jats:bold> Popova <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1069" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1242642">1069</jats:related-article> , published online 7 November; see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1051" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1246250">Chapman</jats:related-article> </jats:bold> ) provide a comprehensive description of this event and of the body that caused it, including detailed information on the asteroid orbit and atmospheric trajectory, damage assessment, and meteorite recovery and characterization. </jats:p>

<jats:title>Lighter Hydrogenation Catalysts</jats:title> <jats:p> Enzymes have evolved to use abundant metals such as iron, cobalt, and nickel for redox catalysis. However, synthetic catalysis has generally relied on the rarer, heavier relatives of these elements: ruthenium, rhodium, iridium, palladium, and platinum (see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1054" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1247240">Bullock</jats:related-article> </jats:bold> ). <jats:bold> Friedfeld <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1076" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1243550">1076</jats:related-article> ) used high-throughput screening to show that the right cobalt precursor can be activated for asymmetric hydrogenation catalysis by using the traditional ligands developed for the precious metals. <jats:bold> Zuo <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1080" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1244466">1080</jats:related-article> ) focused on iron, demonstrating a highly effective asymmetric transfer hydrogenation catalyst that uses a ligand rationally designed after careful mechanistic study. <jats:bold> Jagadeesh <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1073" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1242005">1073</jats:related-article> ) prepared supported iron catalysts that selectively reduce nitro substituents on aromatic rings to amines, thereby facilitating the preparation of a wide range of aniline derivatives. </jats:p>

<jats:title>Lighter Hydrogenation Catalysts</jats:title> <jats:p> Enzymes have evolved to use abundant metals such as iron, cobalt, and nickel for redox catalysis. However, synthetic catalysis has generally relied on the rarer, heavier relatives of these elements: ruthenium, rhodium, iridium, palladium, and platinum (see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1054" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1247240">Bullock</jats:related-article> </jats:bold> ). <jats:bold> Friedfeld <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1076" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1243550">1076</jats:related-article> ) used high-throughput screening to show that the right cobalt precursor can be activated for asymmetric hydrogenation catalysis by using the traditional ligands developed for the precious metals. <jats:bold> Zuo <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1080" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1244466">1080</jats:related-article> ) focused on iron, demonstrating a highly effective asymmetric transfer hydrogenation catalyst that uses a ligand rationally designed after careful mechanistic study. <jats:bold> Jagadeesh <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1073" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1242005">1073</jats:related-article> ) prepared supported iron catalysts that selectively reduce nitro substituents on aromatic rings to amines, thereby facilitating the preparation of a wide range of aniline derivatives. </jats:p>

<jats:title>Lighter Hydrogenation Catalysts</jats:title> <jats:p> Enzymes have evolved to use abundant metals such as iron, cobalt, and nickel for redox catalysis. However, synthetic catalysis has generally relied on the rarer, heavier relatives of these elements: ruthenium, rhodium, iridium, palladium, and platinum (see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1054" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1247240">Bullock</jats:related-article> </jats:bold> ). <jats:bold> Friedfeld <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1076" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1243550">1076</jats:related-article> ) used high-throughput screening to show that the right cobalt precursor can be activated for asymmetric hydrogenation catalysis by using the traditional ligands developed for the precious metals. <jats:bold> Zuo <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1080" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1244466">1080</jats:related-article> ) focused on iron, demonstrating a highly effective asymmetric transfer hydrogenation catalyst that uses a ligand rationally designed after careful mechanistic study. <jats:bold> Jagadeesh <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6162" page="1073" related-article-type="in-this-issue" vol="342" xlink:href="10.1126/science.1242005">1073</jats:related-article> ) prepared supported iron catalysts that selectively reduce nitro substituents on aromatic rings to amines, thereby facilitating the preparation of a wide range of aniline derivatives. </jats:p>