Catálogo de publicaciones - revistas

<jats:title>Challenges for stem cell–based therapies</jats:title> <jats:p> Patient-derived pluripotent stem cells (PSCs) hold promise in the treatment of injury and disease. An ever-increasing number of specific cell types can be generated from PSCs, but technical challenges remain in applying these cells in the clinic. Fox <jats:italic>et al.</jats:italic> review the challenges in attaining this goal. These include gene modification, cell rejection, and delivery and localization issues involved in transplantation of cells for the treatment of diabetes and disorders of the blood, liver, heart, and brain. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.1247391">10.1126/science.1247391</jats:related-article> </jats:p>

<jats:title>Censorship of social media in China</jats:title> <jats:p> Figuring out how many and which social media comments are censored by governments is difficult because those comments, by definition, cannot be read. King <jats:italic>et al.</jats:italic> have posted comments to social media sites in China and then waited to see which of these never appeared, which appeared and were then removed, and which appeared and survived. About 40% of their submissions were reviewed by an army of censors, and more than half of these never appeared. By varying the content of posts across topics, they conclude that any mention of collective action is selectively suppressed. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.1251722">10.1126/science.1251722</jats:related-article> </jats:p>

<jats:p> Reproducibility is the ugly duckling of science. It provokes distress, denial, and passionate calls for action. With $1.5 trillion spent globally each year on R&amp;D, <jats:xref ref-type="fn">*</jats:xref> the idea that 80% of it is irreproducible <jats:xref ref-type="fn">†</jats:xref> can cause downright dread. It threatens the foundations and credibility of the scientific enterprise. But look past the surface, and reproducibility may well be a swan in the making. </jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>The power of the masses proves most unnerving.</jats:p>

<jats:p>New leads in the hunt to explain the global warming hiatus.</jats:p>

<jats:p>The once-sidelined injected vaccine could boost eradication.</jats:p>

<jats:p>Can special algorithms help keep shared bicycles rolling?.</jats:p>

<jats:p>Breeding for dependence, not cooperation, may have driven initial dog domestication.</jats:p>