Catálogo de publicaciones - revistas

<jats:title>Flu vaccine candidate STEMs the tide</jats:title> <jats:p> Every year we need a new flu vaccine, because influenza virus constantly mutates the major target of antibodies to flu: the “head” region of the viral hemagglutinin (HA) protein. Avoiding the problem of mutation requires a vaccine that elicits antibodies against the more conserved “stem” region of HA. During infection, antibodies are occasionally produced that recognize the stem and that neutralize a broad range of influenza virus strains. Impagliazzo <jats:italic>et al.</jats:italic> engineered an HA stem–only vaccine candidate that elicited broadly neutralizing antibodies in mice and nonhuman primates and that protected mice against multiple influenza strains. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6254" page="1301" related-article-type="in-this-issue" vol="349" xlink:href="10.1126/science.aac7263">1301</jats:related-article> </jats:p>

<jats:title>Percolating cluster, factal structure</jats:title> <jats:p> Metallic glasses are appealing materials because they are strong and can bend without breaking. These materials are disordered but possess none of the defects seen in crystalline counterparts. Chen <jats:italic>et al.</jats:italic> developed a model for metallic glasses in which clusters of atoms float free in the liquid, begin to jam, and finally organize into a short-range fractal structure below the glass transition temperature. This model also accounted for the density and high strength characteristics of bulk samples. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6254" page="1306" related-article-type="in-this-issue" vol="349" xlink:href="10.1126/science.aab1233">1306</jats:related-article> </jats:p>