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<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

<jats:p>Celebrating its 120th anniversary in 2016, Shanghai Jiao Tong University (SJTU) remains one of the most prestigious—and oldest—universities in China. During its long history, SJTU has built a tradition of excellence in research and development, particularly in science, engineering, and medicine. This supplement showcases some of the research currently underway at the university, highlighting advances in engineering, physics, bioagriculture, and biomedicine, among others.</jats:p> <jats:p> This special supplement brought to you by the <jats:bold>Science</jats:bold> /AAAS Custom Publishing Office. </jats:p>

<jats:p>Mouse models have been a mainstay in biomedical research for decades. As these models have become more sophisticated, their application has grown and now includes a wide variety of immunodeficient strains that can be used to examine the in vivo growth of human tumors and to test new cancer treatments. One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34+ hematopoietic stem cells. Next-generation NSG models that support human myeloid cell proliferation, such as the NSG-SGM3 mouse, can now provide in vivo conditions that better mimic the natural tumor environment. Human tumor tissue or cell lines can be coengrafted into these mouse models, providing a powerful tool for studying the interactions between human immune cells and human cancers. In this webinar we will discuss the latest advances in mouse models for cancer research and how they are being applied to help us understand the pathways and mechanisms involved in new immune therapies.</jats:p>