Catálogo de publicaciones - revistas

<jats:title>A scavenger that protects the heart</jats:title> <jats:p> Coronary heart disease is a tale of two forms of plasma cholesterol. In contrast to the well-established effects of “bad” cholesterol (LDL-C), the role of “good” cholesterol (HDL-C) is mysterious. Elevated HDL-C correlates with a lower risk of heart disease, yet drugs that raise HDL-C levels do not reduce risk. Zanoni <jats:italic>et al.</jats:italic> found that some people with exceptionally high levels of HDL-C carry a rare sequence variant in the gene encoding the major HDL-C receptor, scavenger receptor BI. This variant destroys the receptor's ability to take up HDL-C. Interestingly, people with this variant have a higher risk of heart disease despite having high levels of HDL-C. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6278" page="1166" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aad3517">1166</jats:related-article> </jats:p>

<jats:title>Describing dispersion forces</jats:title> <jats:p> Dispersion or van der Waals interactions are attractive forces that arise from induced dipoles. They are not seen just in atoms and molecules but also in larger nanostructures and even macroscopic objects. Ambrosetti <jats:italic>et al.</jats:italic> created a qualitatively correct description of van der Waals interactions between polarizable nanostructures over a wide range of finite distances. This required delocalized electrons that have wavelike electron density fluctuations, unlike the more common approaches with dipoles fixed on atoms. Furthermore, the authors observed an enhancement in the nonlocality of the charge density response on the scale of 10 to 20 nm. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6278" page="1171" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aae0509">1171</jats:related-article> </jats:p>

<jats:title>Entangled frequency combs</jats:title> <jats:p> The ability to generate optical frequency combs in which the output light is made up of millions of sharp lines precisely spaced apart has been important for optical applications and for fundamental science. Reimer <jats:italic>et al.</jats:italic> now show that frequency combs can be taken into the quantum regime. They took individual teeth of the combs and quantum-mechanically entangled them to form complex optical states. Because the method is compatible with existing fiber and semiconductor technology, the results demonstrate a possible scalable and practical platform for quantum technologies. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6278" page="1176" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aad8532">1176</jats:related-article> </jats:p>

<jats:title>One model to rule them all?</jats:title> <jats:p>The idea of finding an all-encompassing model to describe the world around us has appealed to generations of scientists. Although we are very far from this ultimate goal, more modest steps can be taken if we focus on particular problems. De las Cuevas and Cubitt used concepts borrowed from computer science to show that all classical spin models (introduced initially to study magnetism) can be solved by tackling a slightly more complex, universal model (see the Perspective by Wehner). Thanks to these findings, it may be possible to physically simulate systems with complex interactions, using the well-understood two-dimensional Ising model with fields.</jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6278" page="1180" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aab3326">1180</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6278" page="1156" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aaf0748">1156</jats:related-article> </jats:p>