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<jats:title>Innate immune crosstalk in T cells</jats:title> <jats:p> The classical view of immune activation is that innate immune cells, such as macrophages and dendritic cells, recognize invading microbes and then alert adaptive immune cells, such as T cells, to respond. Arbore <jats:italic>et al.</jats:italic> now show that innate and adaptive immunity converge in human and mouse T cells. Activated T cells express components of the complement cascade, which in turn leads to the assembly of NLRP3 inflammasomes—both critical components of innate immunity that help hosts detect and eliminate microbes. In T cells, complement and inflammasomes work together to push T cells to differentiate into a specialized subset of T cells important for eliminating intracellular bacteria. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aad1210">10.1126/science.aad1210</jats:related-article> </jats:p>

<jats:p> Next month, the American Association for the Advancement of Science (AAAS) welcomes a new editor-in-chief for the <jats:italic>Science</jats:italic> family of journals, Jeremy M. Berg, as Marcia McNutt steps aside to assume her role as president of the U.S. National Academy of Sciences. This passing of the baton is always an exciting time for AAAS, because it presents an opportunity to refresh views on <jats:italic>Science</jats:italic> 's trajectory in the increasingly complex landscape of science's place in society. In this regard, <jats:italic>Science</jats:italic> and the other <jats:italic>Science</jats:italic> family journals will be in good hands with Jeremy Berg. </jats:p>