Catálogo de publicaciones - revistas

<jats:title>RNAi soothes the path to quiescence</jats:title> <jats:p> Cells, such as those in stem cell niches and immunity memory cells, can exist in a nondividing, quiescent state, from which they can be aroused with the appropriate signal. RNA interference (RNAi) is an important epigenetic pathway in many organisms. Roche <jats:italic>et al.</jats:italic> found that in fission yeast, RNAi was an essential regulator of the quiescent state. RNAi promoted proper chromosome segregation during entry into quiescence. It also prevented inappropriate silencing of the ribosomal DNA during quiescence. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aah5651">10.1126/science.aah5651</jats:related-article> </jats:p>

<jats:p>Last week, member states of the World Health Organization (WHO) advanced another step in the nearly 1-year rigorous process of selecting its next director-general. Candidates for the position presented their vision of international health work and the role of this global health body. Having worked at WHO in a number of capacities in the area of infectious diseases, I know well that international health covers a wide breadth of issues. Add to that noncommunicable diseases and matters such as intellectual property and universal health coverage, and it becomes clear that the next director-general must be a jack of all trades, but also a master of one—leadership in public health. Leadership in this role is about conceiving and articulating a vision, staying faithful to that vision in the face of undue influence, and effectively engaging with not only governments, but with all stakeholders to gain their support and enable the vision to be realized.</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Radioactive tritium promises a bigger bang for Sandia's Z machine but poses safety issues.</jats:p>

<jats:p>New funding shows increased commitment to mystery illness, but not everyone trusts the agency's sincerity.</jats:p>

<jats:p>Agency wants to shed ownership of iconic radio dishes.</jats:p>

<jats:p>Glial cells turn up the volume on pain.</jats:p>

<jats:p> Dangerous <jats:italic>Mycobacterium</jats:italic> strains appear to be spreading. </jats:p>

<jats:p>Archaeologists have a new answer to the mystery of Greenland's Norse, who thrived for centuries and then vanished.</jats:p>